{"id":"W4400193255","doi":"10.1136/gutjnl-2024-bsg.183","title":"P101 The UK IBD BioResource: progressing from genetics to function and clinical translation in Crohn’s disease & ulcerative colitis","year":2024,"lang":"en","type":"article","venue":"Poster presentations","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Nutrasource","funders":"","keywords":"Ulcerative colitis; Crohn's disease; Disease; Function (biology); Inflammatory bowel disease; Translation (biology); Medicine; Immunology; Genetics; Biology; Internal medicine; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001323949,0.0001071014,0.00006532932,0.00005140721,0.0001047374,0.0001831084,0.0000766026,0.00006557152,0.00004010838],"category_scores_gemma":[0.00006562872,0.00009039675,0.00006108162,0.00009226294,0.00009969941,0.00001071092,0.00005806066,0.00009165715,0.00002306245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001098113,"about_ca_system_score_gemma":0.00009343008,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003499966,"about_ca_topic_score_gemma":0.001467084,"domain_scores_codex":[0.9989595,0.0002160152,0.0002440452,0.0003248642,0.0001138213,0.0001417451],"domain_scores_gemma":[0.9994906,0.00007469711,0.00002740327,0.0002214272,0.00004667925,0.0001391597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001429905,0.0001191624,0.9605923,0.00005729624,0.000160246,0.00009046902,0.002571781,0.0003183438,0.003429882,0.0001091242,0.002547136,0.02857431],"study_design_scores_gemma":[0.000355533,0.00002447843,0.9943346,0.00003363168,0.00008230787,9.60007e-7,0.0001269243,0.0007650578,0.0001064422,0.000343903,0.003714126,0.0001119705],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.993874,0.0008960688,0.002987026,0.0009615662,0.0002061212,0.00064843,0.0002186808,0.00001818118,0.0001899289],"genre_scores_gemma":[0.9981137,0.00004450113,0.0003782975,0.0003430962,0.0003197708,0.000121683,0.0004619526,0.00001893933,0.0001980909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03374232,"threshold_uncertainty_score":0.3686273,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03171271047349793,"score_gpt":0.3397596610614616,"score_spread":0.3080469505879637,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}