{"id":"W4400238261","doi":"10.3233/jpd-249007","title":"A Randomized Controlled Trial of Fecal Microbiota Transplantation for Parkinson’s Disease: Getting it right, if not PARFECT","year":2024,"lang":"en","type":"editorial","venue":"Journal of Parkinson s Disease","topic":"Botulinum Toxin and Related Neurological Disorders","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Western Hospital; Toronto General Hospital; University of Toronto; University Health Network","funders":"","keywords":"Parkinson's disease; Fecal bacteriotherapy; Transplantation; Randomized controlled trial; Feces; Medicine; Disease; Internal medicine; Biology; Ecology; Antibiotics; Microbiology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00555191,0.001299907,0.004228794,0.0004897987,0.0006328379,0.00192269,0.001275632,0.004944311,0.01400564],"category_scores_gemma":[0.01828928,0.0004199899,0.002454202,0.0004783164,0.0005692882,0.001011883,0.0003348393,0.006729753,0.001566751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001100823,"about_ca_system_score_gemma":0.001619414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001564341,"about_ca_topic_score_gemma":0.002711991,"domain_scores_codex":[0.9981449,0.001138237,0.0002166068,0.0001722112,0.0002352469,0.00009289705],"domain_scores_gemma":[0.9923555,0.005810791,0.000572202,0.0001539575,0.0005761984,0.0005313116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.4140959,0.002483958,0.0005157698,0.03265541,0.01333218,0.0006507979,0.0001124005,0.000483112,0.001423569,0.00207994,0.4382192,0.0939476],"study_design_scores_gemma":[0.8658473,0.01445799,0.003091752,0.00622604,0.01612921,0.0002557442,0.0001641933,0.001559472,0.000820371,0.002412414,0.08892248,0.0001129977],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"editorial","genre_scores_codex":[0.04419639,0.2095288,0.001190386,0.07420237,0.6427809,0.004725329,0.004257401,0.0005933334,0.01852522],"genre_scores_gemma":[0.3113434,0.1289407,0.007291305,0.1912636,0.2726387,0.01086018,0.002919366,0.0002404253,0.07450235],"genre_candidate":"editorial","genre_consensus":"editorial","teacher_disagreement_score":0.01400564,"threshold_uncertainty_score":0.04685348,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01190863452885911,"score_gpt":0.294447030392555,"score_spread":0.2825383958636959,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}