{"id":"W4400244096","doi":"10.2196/51381","title":"Erlotinib or Gefitinib for Treating Advanced Epidermal Growth Factor Receptor Mutation–Positive Lung Cancer in Aotearoa New Zealand: Protocol for a National Whole-of-Patient-Population Retrospective Cohort Study and Results of a Validation Substudy","year":2024,"lang":"en","type":"article","venue":"JMIR Research Protocols","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Erlotinib; Medicine; Gefitinib; Lung cancer; Population; Cancer registry; Internal medicine; Erlotinib Hydrochloride; Epidermal growth factor receptor; Oncology; Cancer; Environmental health","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.03006541,0.00300467,0.003206135,0.002438716,0.003521686,0.002789731,0.004266548,0.002572689,0.01368833],"category_scores_gemma":[0.02639128,0.002238309,0.004521644,0.003580471,0.002284979,0.002112515,0.002371581,0.002606942,0.00431517],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.01003716,"about_ca_system_score_gemma":0.02952803,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.03790996,"about_ca_topic_score_gemma":0.06242283,"domain_scores_codex":[0.98499,0.007952946,0.002656247,0.001706699,0.001803588,0.0008905293],"domain_scores_gemma":[0.9842667,0.001495712,0.003367672,0.002407423,0.006785946,0.001676382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.3201939,0.02518951,0.1768295,0.04589241,0.009223807,0.004028384,0.00926095,0.008958015,0.01388135,0.01205017,0.2664931,0.1079989],"study_design_scores_gemma":[0.1933035,0.03345351,0.4155475,0.01101049,0.004375363,0.001659251,0.003249235,0.004253997,0.004424682,0.004209599,0.3238323,0.000680541],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.01028632,0.0003121475,0.002056386,0.000302366,0.0001374941,0.9660846,0.01893298,0.0000512057,0.00183662],"genre_scores_gemma":[0.007751219,0.0002348609,0.003015051,0.0002401293,0.00003723787,0.9798549,0.008353703,0.00001052956,0.0005023572],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.03790996,"threshold_uncertainty_score":0.159003,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09334291967005612,"score_gpt":0.5398483479697775,"score_spread":0.4465054282997214,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}