{"id":"W4400272135","doi":"10.1200/jco.2024.42.16_suppl.9554","title":"Pembrolizumab (pembro) for locally advanced (LA) or recurrent/metastatic (R/M) cutaneous squamous cell carcinoma (cSCC): Long-term results of the phase 2 KEYNOTE-629 study.","year":2024,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Jewish General Hospital","funders":"","keywords":"Medicine; Pembrolizumab; Basal cell; Dermatology; Oncology; Internal medicine; Cancer; Immunotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003046505,0.0008452683,0.0008959224,0.0003069431,0.0003983488,0.0007714446,0.0005791117,0.0007680605,0.00334271],"category_scores_gemma":[0.0009484161,0.000297409,0.0007541527,0.0003589015,0.0003675011,0.0008090482,0.0004561563,0.001851869,0.001238286],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006758354,"about_ca_system_score_gemma":0.0009476308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005421351,"about_ca_topic_score_gemma":0.00189276,"domain_scores_codex":[0.9995531,0.000205412,0.0000339447,0.00007553762,0.00006699944,0.0000650055],"domain_scores_gemma":[0.9993293,0.00009028504,0.0002225867,0.00007037679,0.00007075931,0.0002167477],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.544475,0.05454553,0.04449767,0.003399554,0.004435427,0.0006076487,0.0003598075,0.002810264,0.06396113,0.0005284244,0.0249469,0.2554326],"study_design_scores_gemma":[0.4071122,0.4425825,0.1126585,0.000387032,0.003186884,0.001602774,0.0001628767,0.001730776,0.008041511,0.0004449701,0.02201317,0.00007682767],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729401,0.01054333,0.001073349,0.0006062675,0.0001263543,0.00367041,0.005728148,0.0001603876,0.00515168],"genre_scores_gemma":[0.9796004,0.003755129,0.001586453,0.001226365,0.0001654772,0.002565405,0.008348754,0.00003404582,0.002718031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00334271,"threshold_uncertainty_score":0.01611161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09897449490993147,"score_gpt":0.4716128087527178,"score_spread":0.3726383138427863,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}