{"id":"W4400280485","doi":"10.1073/pnas.2402543121","title":"POTRA domains of the TamA insertase interact with the outer membrane and modulate membrane properties","year":2024,"lang":"en","type":"article","venue":"Proceedings of the National Academy of Sciences","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada; University of Toronto; Université Laval; Institut National de la Recherche Scientifique; Centre hospitalier universitaire de Québec; PROTEO; Université du Québec à Montréal","funders":"Fonds de recherche du Québec – Nature et technologies; Fonds de recherche du Québec; Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Compute Canada; Institut national de la recherche scientifique","keywords":"Membrane; Biophysics; Cell biology; Chemistry; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001025797,0.0003121518,0.0001970277,0.00007860135,0.0001286926,0.0003010405,0.0002827618,0.0003198552,0.001173917],"category_scores_gemma":[0.0001870449,0.0001332204,0.0002166149,0.00007455431,0.0002189424,0.0003990586,0.0002850403,0.0005279109,0.0003340135],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002227952,"about_ca_system_score_gemma":0.0001166289,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002235054,"about_ca_topic_score_gemma":0.0002215131,"domain_scores_codex":[0.9999355,0.000008202382,0.00000406351,0.00001654732,0.0000196269,0.00001604372],"domain_scores_gemma":[0.9999378,0.00001316118,0.00001755758,0.000006664867,0.000006059028,0.00001880535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003082184,0.00008556567,0.001353338,0.00004789438,0.00001670262,0.0001441322,0.00002546641,0.001357417,0.9941196,0.0004757832,0.00008751289,0.001978346],"study_design_scores_gemma":[0.0001100949,0.0006946006,0.0180501,0.00001438407,0.00004710431,0.000691148,0.0001122188,0.03771427,0.9383819,0.0005554727,0.003590796,0.00003798303],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9972746,0.0003446715,0.00179032,0.00004377748,0.000009464601,0.000006864885,0.00005990329,0.00004600305,0.0004243722],"genre_scores_gemma":[0.9977756,0.000213594,0.001246108,0.00004273923,0.00000417133,0.00001152456,0.0001703533,0.00001484776,0.0005209269],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001173917,"threshold_uncertainty_score":0.003927112,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01813250973904297,"score_gpt":0.2430740784934091,"score_spread":0.2249415687543662,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}