{"id":"W4400297015","doi":"10.1093/humrep/deae108.788","title":"P-439 Analysis of Products of Conception (POC) using Whole Genome Next Generation Sequencing (NGS) in pregnancy loss after euploid or mosaic embryo transfer","year":2024,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"CReATe Fertility Centre","funders":"","keywords":"Embryo transfer; Biology; Ploidy; Products of conception; Embryo; Genome; Mosaic; Whole genome sequencing; Pregnancy; Genetics; Gestation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001604886,0.0002112095,0.0002504182,0.000962263,0.0002790145,0.0007200049,0.0003060633,0.0003807692,0.001697134],"category_scores_gemma":[0.00357798,0.000154064,0.0002488165,0.0005779339,0.0004686094,0.0002112244,0.0003822664,0.0003191829,0.0003591503],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004190415,"about_ca_system_score_gemma":0.0003726007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002294018,"about_ca_topic_score_gemma":0.001316543,"domain_scores_codex":[0.9990795,0.0002175592,0.00008311206,0.0001339597,0.0003863723,0.00009954671],"domain_scores_gemma":[0.9985265,0.0006629078,0.0003942926,0.0001087095,0.0002225846,0.00008506065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00138752,0.00006036768,0.9106744,0.0003250723,0.0001090433,0.01136052,0.0008632758,0.0005417617,0.02175394,0.0004103153,0.001222944,0.05129088],"study_design_scores_gemma":[0.00004115618,0.0006083134,0.9218923,0.0002314059,0.0002253852,0.03314393,0.001247058,0.005111559,0.02549479,0.001010316,0.01096678,0.00002702643],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899631,0.003373151,0.002574435,0.0002319456,0.00003198409,0.00008340657,0.001169811,0.00003610607,0.002536069],"genre_scores_gemma":[0.9962948,0.0008417728,0.001457039,0.0001264648,0.00001246702,0.00005132253,0.0005494972,0.00001628466,0.000650275],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002294018,"threshold_uncertainty_score":0.008487523,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1094420895551118,"score_gpt":0.3151542046606596,"score_spread":0.2057121151055478,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}