{"id":"W4400340032","doi":"10.1186/s12967-024-05410-5","title":"Cardiopulmonary and metabolic responses during a 2-day CPET in myalgic encephalomyelitis/chronic fatigue syndrome: translating reduced oxygen consumption to impairment status to treatment considerations","year":2024,"lang":"en","type":"article","venue":"Journal of Translational Medicine","topic":"Fibromyalgia and Chronic Fatigue Syndrome Research","field":"Medicine","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Francis Xavier University","funders":"National Institute of Neurological Disorders and Stroke; National Institutes of Health; National Heart, Lung, and Blood Institute; Weill Cornell Medical College; National Institute of Allergy and Infectious Diseases; Quest Diagnostics; National Center for Advancing Translational Sciences; Foundation for the National Institutes of Health","keywords":"Chronic fatigue syndrome; Encephalomyelitis; Medicine; Physical therapy; Intensive care medicine; Immunology; Multiple sclerosis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009712864,0.0002889529,0.0007961892,0.001359732,0.0001241275,0.0000417258,0.0000649168,0.0001006038,0.0005638426],"category_scores_gemma":[0.0001989027,0.000222665,0.0001673688,0.0004395354,0.00013353,0.0002240109,0.00001271689,0.0003924646,0.00001505674],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000608836,"about_ca_system_score_gemma":0.001376355,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001134821,"about_ca_topic_score_gemma":0.00003430722,"domain_scores_codex":[0.996848,0.0002760452,0.001075279,0.0003785703,0.0009236943,0.0004983353],"domain_scores_gemma":[0.9983235,0.0005946636,0.00008803196,0.0001814863,0.0001747722,0.0006375283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.005272835,0.0008507171,0.04106557,0.009894786,0.003323681,0.02268202,0.06292256,0.009810619,0.7889504,0.002025821,0.0005708772,0.05263004],"study_design_scores_gemma":[0.007253674,0.006198527,0.9537289,0.0107008,0.0005383694,0.01606048,0.0006284543,0.001257009,0.001828414,0.0005585608,0.0009104127,0.0003364676],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9379702,0.03669057,0.0005154202,0.02343224,0.0002484287,0.0009869537,0.00005887982,0.00003002113,0.00006724644],"genre_scores_gemma":[0.9953459,0.001740963,0.002379899,0.00003099471,0.0002041744,0.00006317694,0.00002699048,0.00003654267,0.0001713446],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9126633,"threshold_uncertainty_score":0.9080017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04536007119769558,"score_gpt":0.3479336594833212,"score_spread":0.3025735882856256,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}