{"id":"W4400345718","doi":"10.1097/icb.0000000000001619","title":"SYSTEMIC ANTI-VEGF BIOSIMILAR THERAPY ASSOCIATED WITH IMPROVED MACULAR ANATOMY AND DURATION OF EFFECT IN A PATIENT WITH NEARLY RECALCITRANT NEOVASCULAR AGE-RELATED MACULAR DEGENERATION","year":2024,"lang":"en","type":"article","venue":"Retinal Cases & Brief Reports","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canadian Research Institute for the Advancement of Women","funders":"Research to Prevent Blindness","keywords":"Medicine; Macular degeneration; Ophthalmology; Biosimilar; Ranibizumab; Surgery; Bevacizumab; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004210341,0.0003521942,0.0006572425,0.0002087902,0.00007325062,0.00008747514,0.00002774743,0.0001527529,0.0000167966],"category_scores_gemma":[0.00009919969,0.000230786,0.0001914179,0.0006000662,0.0001154236,0.0001451406,0.00001471928,0.0001947434,5.386891e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001680171,"about_ca_system_score_gemma":0.0002041262,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005370929,"about_ca_topic_score_gemma":0.00003157512,"domain_scores_codex":[0.9975537,0.0002190282,0.0007276869,0.000640569,0.0005678187,0.0002911833],"domain_scores_gemma":[0.9988856,0.00007333248,0.0003379875,0.0003490649,0.000190804,0.000163244],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.004182674,0.0007754238,0.3606906,0.001553353,0.002651907,0.5107874,0.0006833677,0.0001532621,0.1076657,0.00005345434,0.00003682954,0.01076607],"study_design_scores_gemma":[0.01511183,0.03470452,0.5989342,0.02376741,0.006629326,0.1586624,0.0003128336,0.01247377,0.1472196,0.0001169413,0.0003818448,0.001685297],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9845515,0.01325913,0.00004655949,0.00008610522,0.00005050878,0.00184862,0.00001618622,0.00009038206,0.00005100189],"genre_scores_gemma":[0.9987646,0.0004912727,0.00009975422,0.00004240579,0.0000194294,0.0001052969,0.0003897944,0.00005990156,0.00002748771],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.352125,"threshold_uncertainty_score":0.9411182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006257155639567261,"score_gpt":0.2430000494939353,"score_spread":0.2367428938543681,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}