{"id":"W4400382706","doi":"10.1002/adfm.202403910","title":"Gemcitabine‐Loaded Injectable Hydrogel for Localized Breast Cancer Immunotherapy","year":2024,"lang":"en","type":"article","venue":"Advanced Functional Materials","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Victoria","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Iran University of Medical Sciences; British Columbia Knowledge Development Fund; University of Victoria","keywords":"Tumor microenvironment; Cancer research; Immunotherapy; Population; Immune system; CD8; Materials science; Self-healing hydrogels; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0002656402,0.0003207436,0.0004422491,0.0001724626,0.0002439959,0.00008349826,0.0001785078,0.0002456671,0.008846258],"category_scores_gemma":[0.00002622783,0.0002684629,0.0001825975,0.0002079141,0.0001549176,0.0005059768,0.00003509153,0.0001449105,0.0003473825],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008279322,"about_ca_system_score_gemma":0.0001660792,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000578345,"about_ca_topic_score_gemma":9.904127e-7,"domain_scores_codex":[0.9983802,0.0001183882,0.0004806255,0.0004591027,0.00005457309,0.0005070845],"domain_scores_gemma":[0.999162,0.0003579985,0.00009621322,0.0002788877,0.0000874293,0.00001751514],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009062011,0.0000757852,0.00001012264,0.00008134729,0.0006226993,0.000001901424,0.00006617665,0.00008231182,0.9636583,0.007553621,0.002026753,0.01675899],"study_design_scores_gemma":[0.002480254,0.0001587787,0.0007070464,0.0001263247,0.00003904852,0.00014887,0.00003976424,0.000004315593,0.7490635,0.001176947,0.2457761,0.0002790064],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8979417,0.07108519,0.008043842,0.001530106,0.01695232,0.001276256,0.001802972,0.001124014,0.0002435659],"genre_scores_gemma":[0.9837579,0.001666094,0.0002314183,0.0007578795,0.0002626851,0.001144807,0.0004964831,0.0001377642,0.01154501],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2437494,"threshold_uncertainty_score":0.9999768,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01169510344917817,"score_gpt":0.2606770253727532,"score_spread":0.248981921923575,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}