{"id":"W4400428906","doi":"10.1038/s41408-024-01084-w","title":"Autologous transplant vs. CAR-T therapy in patients with DLBCL treated while in complete remission","year":2024,"lang":"en","type":"article","venue":"Blood Cancer Journal","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; MorphoSys; Swedish Orphan Biovitrum; Vertex Pharmaceuticals; Omeros Corporation; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Jazz Pharmaceuticals; StemCyte; Actinium Pharmaceuticals; CareDx; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; CSL Behring; BeiGene; HistoGenetics; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences; Sanofi; GlaxoSmithKline; Gateway for Cancer Research; Mallinckrodt Pharmaceuticals; Astellas Pharma US; Amgen","keywords":"Medicine; Cumulative incidence; Internal medicine; Univariate analysis; Incidence (geometry); Progression-free survival; Hematopoietic cell; Surgery; Retrospective cohort study; Hematopoietic stem cell transplantation; Transplantation; Multivariate analysis; Chemotherapy; Haematopoiesis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003055788,0.0001902197,0.0003863756,0.0003940751,0.0000559812,0.00006026892,0.0001231486,0.0001028502,0.002159376],"category_scores_gemma":[0.000005779332,0.0001258985,0.0000816396,0.0005488389,0.00005178665,0.00008993215,0.000009601227,0.0009242599,0.000006373033],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003144313,"about_ca_system_score_gemma":0.0004488724,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006733788,"about_ca_topic_score_gemma":0.0004365526,"domain_scores_codex":[0.998252,0.0001231893,0.0003472503,0.000280058,0.0005547003,0.0004428292],"domain_scores_gemma":[0.9994379,0.00004958126,0.00004686544,0.0001713929,0.00009351427,0.0002007131],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0055346,0.0007314117,0.8858428,0.00009325616,0.0002718301,0.002047999,0.001577783,0.00004170498,0.0225972,0.000003189693,0.0005613597,0.08069688],"study_design_scores_gemma":[0.02634117,0.003000429,0.9447457,0.002796919,0.0001058616,0.0006942879,0.00005412388,0.0004523795,0.006482588,0.00002624183,0.01502863,0.0002716838],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936263,0.003977149,0.000005035023,0.000948158,0.0001610455,0.0004495466,0.00003589581,0.00004009238,0.0007567614],"genre_scores_gemma":[0.9957082,0.00308349,0.00005063312,0.0001745732,0.0001876964,0.00003080897,0.00002490517,0.0000488982,0.0006908324],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0804252,"threshold_uncertainty_score":0.9987528,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02750997811990137,"score_gpt":0.2966512924150291,"score_spread":0.2691413142951278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}