{"id":"W4400428906","doi":"10.1038/s41408-024-01084-w","title":"Autologous transplant vs. CAR-T therapy in patients with DLBCL treated while in complete remission","year":2024,"lang":"en","type":"article","venue":"Blood Cancer Journal","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Environmental Health Sciences; National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Takeda Oncology; Health Resources and Services Administration; MorphoSys; Swedish Orphan Biovitrum; Vertex Pharmaceuticals; Omeros Corporation; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; Jazz Pharmaceuticals; StemCyte; Actinium Pharmaceuticals; CareDx; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; CSL Behring; BeiGene; HistoGenetics; Atara Biotherapeutics; National Cancer Institute; Gilead Sciences; Sanofi; GlaxoSmithKline; Gateway for Cancer Research; Mallinckrodt Pharmaceuticals; Astellas Pharma US; Amgen","keywords":"Medicine; Cumulative incidence; Internal medicine; Univariate analysis; Incidence (geometry); Progression-free survival; Hematopoietic cell; Surgery; Retrospective cohort study; Hematopoietic stem cell transplantation; Transplantation; Multivariate analysis; Chemotherapy; Haematopoiesis","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005718106,0.0001055579,0.0005000486,0.0001833734,0.0001291461,0.0003295835,0.0001462652,0.0002390747,0.000546923],"category_scores_gemma":[0.001055353,0.00008238395,0.0005893242,0.0002887215,0.0001573498,0.000217282,0.0001679014,0.0003750942,0.00008564408],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003348613,"about_ca_system_score_gemma":0.0002766193,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005329138,"about_ca_topic_score_gemma":0.0009204251,"domain_scores_codex":[0.9997129,0.0001194747,0.00003341717,0.00005814042,0.00003095985,0.00004514317],"domain_scores_gemma":[0.9992747,0.0002386499,0.0002728692,0.00003692907,0.00002131075,0.00015555],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1726865,0.00255414,0.7464077,0.0003104543,0.001239957,0.0006901239,0.0001996987,0.001136216,0.006424726,0.0001523746,0.0006089575,0.06758923],"study_design_scores_gemma":[0.007563706,0.07455738,0.9091652,0.0000616992,0.001095948,0.001707968,0.0002001162,0.002073721,0.001649744,0.0002572715,0.001647968,0.00001932966],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991702,0.0005683713,0.00003754907,0.00002243321,0.000007485318,0.000009427524,0.00005604595,0.000001596579,0.0001268724],"genre_scores_gemma":[0.9995789,0.0001755581,0.0000304155,0.0000395287,0.00001648005,0.000007594707,0.0001145282,5.281529e-7,0.00003652886],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005718106,"threshold_uncertainty_score":0.003024101,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02750997811990137,"score_gpt":0.2966512924150291,"score_spread":0.2691413142951278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}