{"id":"W4400451487","doi":"10.3390/reprodmed5030011","title":"Temporal Evaluation of a Minimally Invasive Method of Preimplantation Genetic Testing for Aneuploidy (mi-PGT-A) in Human Embryos","year":2024,"lang":"en","type":"article","venue":"Reproductive Medicine","topic":"Prenatal Screening and Diagnostics","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Guelph; McMaster University; CReATe Fertility Centre","funders":"McMaster University","keywords":"Aneuploidy; Embryo; Genetic testing; Biology; Andrology; Genetics; Medicine; Chromosome; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.002649827,0.0001334524,0.0004258617,0.0003283563,0.00002371751,0.000002925791,0.00006378979,0.00006412985,0.00002738948],"category_scores_gemma":[0.01707884,0.0001090469,0.0000480685,0.0005315776,0.0001286073,0.00006338527,0.00002647081,0.0001343207,7.786402e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008285612,"about_ca_system_score_gemma":0.0003148896,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005987265,"about_ca_topic_score_gemma":0.00005514442,"domain_scores_codex":[0.9980761,0.0001644798,0.0005779046,0.0004882507,0.0005395457,0.0001536924],"domain_scores_gemma":[0.9973627,0.001274347,0.0002092302,0.0003127432,0.0007844734,0.00005654225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0005119123,0.0002314647,0.08635908,0.003099369,0.0001901213,0.00005364232,0.004462059,0.0008742255,0.8184386,0.0002854542,0.000833079,0.084661],"study_design_scores_gemma":[0.004711688,0.005619369,0.6187331,0.006002359,0.001591983,0.0003072805,0.001336016,0.01413441,0.3414753,0.00582932,0.00004804534,0.0002111112],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898878,0.002449311,0.004232139,0.0006626815,0.0001595042,0.00146738,0.00002637823,0.00003963017,0.00107523],"genre_scores_gemma":[0.9682425,0.00001122739,0.0309435,0.00002426312,0.0004584327,0.000108015,0.0001304953,0.00002274168,0.00005885154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.532374,"threshold_uncertainty_score":0.9912007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1236304108715104,"score_gpt":0.4132166969771684,"score_spread":0.289586286105658,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}