{"id":"W4400457748","doi":"10.1128/mbio.01535-24","title":"The spliceosome impacts morphogenesis in the human fungal pathogen <i>Candida albicans</i>","year":2024,"lang":"en","type":"article","venue":"mBio","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Genome Canada; Canadian Institutes of Health Research; National Institutes of Health; National Institute of Allergy and Infectious Diseases; Natural Sciences and Engineering Research Council of Canada; Canadian Institute for Advanced Research","keywords":"Filamentation; Spliceosome; Candida albicans; Biology; RNA splicing; Intron; Corpus albicans; Gene; Virulence; Genetics; Mutant; Microbiology; Cell biology; RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001103311,0.0002270401,0.0001517385,0.0001730791,0.0002092998,0.0004460793,0.0001527182,0.0002615015,0.001390322],"category_scores_gemma":[0.0001609406,0.00009635834,0.0002699271,0.0001329187,0.0001698998,0.00009103891,0.0002409565,0.0004110818,0.0003164058],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003074662,"about_ca_system_score_gemma":0.000289776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002091188,"about_ca_topic_score_gemma":0.002414894,"domain_scores_codex":[0.9998456,0.00002014031,0.00001250139,0.00003912629,0.00004769056,0.00003486418],"domain_scores_gemma":[0.9999006,0.00001722871,0.0000364951,0.000009776662,0.0000162018,0.00001974524],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009468156,0.00001288377,0.0008457744,0.00003000487,0.000004844222,0.00005146598,0.000006877382,0.00006004447,0.9977048,0.00005024439,0.0001067433,0.00103158],"study_design_scores_gemma":[0.00001189384,0.0002864469,0.06298119,0.00003115506,0.00004850856,0.0005138873,0.0001209452,0.002113473,0.9304504,0.0001165825,0.003310903,0.00001462991],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953342,0.001056599,0.0009546321,0.0001383034,0.00003274682,0.00001828957,0.001128711,0.0000863918,0.001250182],"genre_scores_gemma":[0.9966255,0.0004372207,0.001064323,0.0001451992,0.000006787335,0.00001320124,0.0009496728,0.00003040043,0.0007276417],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002091188,"threshold_uncertainty_score":0.00465107,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01531876887231148,"score_gpt":0.305716825751751,"score_spread":0.2903980568794395,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}