{"id":"W4400484292","doi":"10.1042/bcj20210352","title":"The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death","year":2024,"lang":"en","type":"review","venue":"Biochemical Journal","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; University of Toronto; Sunnybrook Health Science Centre","funders":"","keywords":"Cell biology; Biology; Apoptosis; Bcl-2 family; Programmed cell death; Activator (genetics); Protein family; Intracellular; Cell; Mitochondrion; Bacterial outer membrane; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003649857,0.0003631702,0.0005400843,0.0000838142,0.0001807837,0.0001267839,0.0004736298,0.0004032876,0.00001455761],"category_scores_gemma":[0.00002879307,0.0002006508,0.0007689263,0.0001074585,0.0001333914,0.000005569087,0.000184157,0.0005723144,0.00001919802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005431449,"about_ca_system_score_gemma":0.0003829221,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003618587,"about_ca_topic_score_gemma":0.00000161511,"domain_scores_codex":[0.9982474,0.0001289719,0.0006547331,0.0003614283,0.0003071689,0.0003002927],"domain_scores_gemma":[0.9988028,0.00003465365,0.0005632182,0.0003472011,0.000104527,0.0001476468],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00004956735,0.00009955539,0.000001087098,0.004028078,0.0004175313,0.00008625423,0.00002824874,0.000001579397,0.4824473,0.00009736775,0.01043931,0.5023041],"study_design_scores_gemma":[0.000112557,0.0001268617,0.000001551285,0.003038093,0.0007000839,0.00121982,0.00002720934,0.00001039942,0.0365265,0.0002498534,0.9577072,0.0002798668],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001626055,0.996502,0.0002424513,0.00004365169,0.0009663751,0.0003269682,0.00004219141,0.000009174159,0.0002411056],"genre_scores_gemma":[0.002278261,0.9935374,0.0005387985,0.00001188278,0.001120043,0.00003682962,0.0001232971,0.00005025044,0.002303183],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9472679,"threshold_uncertainty_score":0.8182304,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04245024798778463,"score_gpt":0.3257012965233517,"score_spread":0.2832510485355671,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}