{"id":"W4400512022","doi":"10.3389/frhem.2024.1413794","title":"Case report: Aggressive natural killer cell leukemia and refractory hemophagocytic lymphohistiocytosis in an adolescent","year":2024,"lang":"en","type":"article","venue":"Frontiers in Hematology","topic":"Autoimmune and Inflammatory Disorders Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Dalhousie University; Terry Fox Research Institute; Spinal Cord Injury BC; University of British Columbia","funders":"NHLBI Division of Intramural Research; National Institute of Allergy and Infectious Diseases","keywords":"Hemophagocytic lymphohistiocytosis; Medicine; Fulminant; Lymphoma; Malignancy; Bone marrow; Leukemia; Etoposide; Aggressive lymphoma; Immunology; Disease; Pathology; Chemotherapy; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002520951,0.001382419,0.00121943,0.001796209,0.00188172,0.001280916,0.0009041029,0.004070358,0.002570198],"category_scores_gemma":[0.001709996,0.0007927468,0.0009174891,0.001017504,0.001257077,0.00205277,0.001558109,0.003066459,0.0009456474],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009553932,"about_ca_system_score_gemma":0.0008179666,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001772056,"about_ca_topic_score_gemma":0.002512213,"domain_scores_codex":[0.9995168,0.00004998334,0.00005596886,0.0001713439,0.00006967391,0.0001361712],"domain_scores_gemma":[0.9991477,0.0002172127,0.0001918004,0.00005092324,0.00005654375,0.0003358749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00001422968,0.00004214447,0.006328336,0.00003037174,0.000006555957,0.9907585,0.000221095,0.00008951174,0.0004491707,0.0003340157,0.00028588,0.001440038],"study_design_scores_gemma":[0.000005398032,0.00002590168,0.002470216,0.00001527446,0.000006187528,0.9963051,0.000103424,0.0001337689,0.0001606539,0.0001853333,0.0005828095,0.000005818135],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9667293,0.006837403,0.007411487,0.005256484,0.000639682,0.0003181958,0.00067337,0.000200999,0.011933],"genre_scores_gemma":[0.9935383,0.001440595,0.002045227,0.0008214869,0.0005972291,0.00003522585,0.00009914889,0.00002641371,0.001396279],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004070358,"threshold_uncertainty_score":0.008598208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01388834963660866,"score_gpt":0.2905274416755456,"score_spread":0.2766390920389369,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}