{"id":"W4400517861","doi":"10.1093/jac/dkae197","title":"Breakthrough HIV viraemia on bictegravir/emtricitabine/tenofovir alafenamide in the third trimester of pregnancy","year":2024,"lang":"en","type":"article","venue":"Journal of Antimicrobial Chemotherapy","topic":"HIV/AIDS drug development and treatment","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Hospital","funders":"","keywords":"Emtricitabine; Tenofovir alafenamide; Human immunodeficiency virus (HIV); Virology; Medicine; Pregnancy; Didanosine; Obstetrics; Gynecology; Sida; Biology; Antiretroviral therapy; Viral disease; Viral load","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001253862,0.0004775305,0.0004862864,0.0006365168,0.001061235,0.0005188828,0.0004420691,0.001320251,0.00192391],"category_scores_gemma":[0.001724406,0.0003226825,0.0004292498,0.0003557451,0.0004738013,0.000459409,0.0004098985,0.002138554,0.0003671081],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001111949,"about_ca_system_score_gemma":0.0006082252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.008533488,"about_ca_topic_score_gemma":0.01143098,"domain_scores_codex":[0.9997609,0.00002719637,0.00001937297,0.00005314045,0.00005750113,0.00008192223],"domain_scores_gemma":[0.9997231,0.00007555413,0.00006590584,0.00001442825,0.00001935102,0.000101627],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00008298281,0.00005481487,0.01407797,0.00004418268,0.00001118949,0.9737659,0.0005839238,0.0001413576,0.002361509,0.0003093925,0.000875532,0.007691273],"study_design_scores_gemma":[0.000008428286,0.0002275641,0.01322713,0.0000988571,0.00001789998,0.9816267,0.0003398983,0.0003877498,0.001198232,0.000342707,0.002506731,0.00001803903],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9400874,0.0111417,0.003471755,0.009987594,0.0005606501,0.0002994037,0.0005920845,0.0002713817,0.03358782],"genre_scores_gemma":[0.9914705,0.003067521,0.0005762937,0.00127685,0.0001428291,0.00001808286,0.00009484299,0.00002366877,0.003329448],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008533488,"threshold_uncertainty_score":0.01696759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01196506794122019,"score_gpt":0.2735159858365322,"score_spread":0.261550917895312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}