{"id":"W4400526195","doi":"10.17975/sfj-2024-007","title":"CRISPR technology for Parkinson’s disease: Recent advancements and ongoing challenges","year":2024,"lang":"en","type":"article","venue":"STEM Fellowship Journal","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"CRISPR; Parkinson's disease; Disease; Computational biology; Biology; Computer science; Medicine; Genetics; Gene; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007841716,0.0007513035,0.00108101,0.002100782,0.0007048639,0.003315045,0.0009449076,0.00183566,0.00351799],"category_scores_gemma":[0.005746627,0.000355504,0.0008359935,0.001570856,0.001686767,0.004023843,0.001678326,0.002952165,0.001518379],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00122088,"about_ca_system_score_gemma":0.002980333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009256472,"about_ca_topic_score_gemma":0.001443544,"domain_scores_codex":[0.9970859,0.0007904145,0.0003453852,0.000434003,0.001113277,0.0002310767],"domain_scores_gemma":[0.9946529,0.002676759,0.0003932761,0.0002632582,0.001528942,0.0004848685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002386674,0.0001231991,0.001801433,0.00600166,0.00008353846,0.0003564318,0.0004376103,0.0009321758,0.02095897,0.02724135,0.03291427,0.9089108],"study_design_scores_gemma":[0.00003555228,0.0006633602,0.002548605,0.003295962,0.0001850472,0.001803932,0.0005303694,0.001299126,0.01730873,0.02162929,0.950587,0.0001130815],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007067619,0.9333041,0.02023111,0.0244715,0.002508974,0.000120941,0.0002908757,0.0005078802,0.01149693],"genre_scores_gemma":[0.02486989,0.94153,0.02222627,0.006002585,0.001770004,0.0001168642,0.0005053433,0.0001480451,0.002831036],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.007841716,"threshold_uncertainty_score":0.04147148,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01952117277488391,"score_gpt":0.3237027961473408,"score_spread":0.3041816233724569,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}