{"id":"W4400577795","doi":"10.1093/genetics/iyae111","title":"Impacts of pleiotropy and migration on repeated genetic adaptation","year":2024,"lang":"en","type":"article","venue":"Genetics","topic":"Genetic diversity and population structure","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Human Frontier Science Program","keywords":"Biology; Pleiotropy; Genetics; Adaptation (eye); Evolutionary biology; Phenotype; Gene; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000432212,0.00009131132,0.00006994426,0.00005688392,0.00003285458,0.00002522865,0.00005185828,0.0001065239,0.00001707153],"category_scores_gemma":[0.00001950313,0.00008820554,0.00003561605,0.00008146928,0.00003873037,0.000001686266,0.00002959028,0.00004169732,0.000005945105],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004917565,"about_ca_system_score_gemma":0.0000351118,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001927436,"about_ca_topic_score_gemma":0.00008172806,"domain_scores_codex":[0.9994265,0.00002819248,0.0001375697,0.0002037978,0.0001092403,0.00009474233],"domain_scores_gemma":[0.9996952,0.000007052255,0.00003738838,0.0001612777,0.00005073708,0.00004834664],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001109057,0.00002740719,0.02406913,0.0001382674,0.0001106199,0.000006582777,0.0008200715,0.009392958,0.9136862,0.0004282226,0.003517266,0.04769234],"study_design_scores_gemma":[0.0007807052,0.001607509,0.351704,0.0001026597,0.0001453931,0.00005819505,0.0002824865,0.01482483,0.5638506,0.0009313533,0.06523371,0.0004786022],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947181,0.002265715,0.002485336,0.0001038847,0.000148916,0.00009761851,0.00003252698,0.00001128142,0.0001366594],"genre_scores_gemma":[0.9944564,0.0007159935,0.004399238,0.00006952811,0.00009870015,0.000001499316,0.0001108138,0.00001088212,0.0001369282],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3498356,"threshold_uncertainty_score":0.3596917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01240164798530597,"score_gpt":0.2381564731096163,"score_spread":0.2257548251243103,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}