{"id":"W4400621681","doi":"10.1111/imm.13836","title":"Polygenic <scp>TB</scp> control and the sequence of innate/adaptive immune responses to infection: <scp>MHC</scp>‐<scp>II</scp> alleles determine the size of the <scp>S100A8</scp>/9‐producing neutrophil population","year":2024,"lang":"en","type":"article","venue":"Immunology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Russian Science Foundation; McGill University","keywords":"Biology; Major histocompatibility complex; Congenic; Phenotype; Population; Immunology; Immune system; Acquired immune system; Allele; S100A8; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001303276,0.0002576126,0.0001445758,0.0003880434,0.0001274377,0.0002234483,0.0001461265,0.0001992597,0.001609453],"category_scores_gemma":[0.0001044798,0.0001183661,0.0001429178,0.0001417716,0.0002700023,0.00009523039,0.0002688002,0.0004767581,0.0002139328],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001348083,"about_ca_system_score_gemma":0.0000947823,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005377242,"about_ca_topic_score_gemma":0.001204806,"domain_scores_codex":[0.9998356,0.00003267255,0.00001434124,0.00004778934,0.00003697783,0.00003267713],"domain_scores_gemma":[0.9996462,0.00005744602,0.0001471399,0.00003784341,0.00001738122,0.00009395974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007976747,0.00001925089,0.001917769,0.000005231236,0.000005895435,0.00005402585,0.000009738505,0.00002084462,0.9973618,0.00003228936,0.000009661852,0.0004836497],"study_design_scores_gemma":[0.00006236678,0.0008371341,0.593554,0.00001729407,0.00008235462,0.00199307,0.0001184126,0.001959486,0.3997137,0.0001784785,0.001465719,0.00001797489],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986932,0.00009388001,0.0007062434,0.00001803854,0.000002478471,0.000007252032,0.0001739011,0.00001818582,0.0002867973],"genre_scores_gemma":[0.9981888,0.000076993,0.0006665315,0.00002712048,0.000005025513,0.00001903829,0.0002429973,0.00002452076,0.0007489193],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001609453,"threshold_uncertainty_score":0.005384147,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01100174170612571,"score_gpt":0.2352698947286527,"score_spread":0.224268153022527,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}