{"id":"W4400654813","doi":"10.3899/jrheum.2024-0317","title":"Debate at the GRAPPA 2023 Annual Meeting: Should Methotrexate Be the First Systemic Therapy in Psoriatic Disease?","year":2024,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Psoriasis: Treatment and Pathogenesis","field":"Immunology and Microbiology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Center for Advancing Translational Sciences; National Institutes of Health; Celgene; Amgen; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Psoriatic arthritis; Systemic therapy; Medicine; Psoriasis; Tolerability; Methotrexate; Clinical trial; Disease; Internal medicine; Intensive care medicine; Dermatology; Adverse effect","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.05514075,0.0006696912,0.002392124,0.001397554,0.005176971,0.008288866,0.002958831,0.03762741,0.004827598],"category_scores_gemma":[0.1059488,0.0009128989,0.001687618,0.001577255,0.01544424,0.01095011,0.0040376,0.0585053,0.003581213],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005393268,"about_ca_system_score_gemma":0.008876883,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002571221,"about_ca_topic_score_gemma":0.002840448,"domain_scores_codex":[0.9764658,0.01179217,0.002644204,0.002042217,0.005926519,0.001129082],"domain_scores_gemma":[0.9000699,0.07308721,0.004945384,0.002071288,0.0115552,0.00827102],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003839883,0.00008793434,0.0007800274,0.0006240377,0.0001269793,0.0005290864,0.00225104,0.0001347001,0.0006896955,0.05221963,0.8546314,0.08754155],"study_design_scores_gemma":[0.000211506,0.0001587134,0.00104365,0.00283085,0.0001350263,0.001131236,0.002546751,0.000186584,0.0003720172,0.05331453,0.9379502,0.0001190254],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002454652,0.01069626,0.0002216409,0.9733235,0.01460982,0.00000410886,0.00001669617,0.000006135416,0.0008763891],"genre_scores_gemma":[0.01192204,0.0174112,0.001079501,0.9046547,0.06347132,0.00002682401,0.00003433727,0.00004032722,0.001359753],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.05514075,"threshold_uncertainty_score":0.2916157,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02571237134135336,"score_gpt":0.2665038562401503,"score_spread":0.2407914848987969,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}