{"id":"W4400664116","doi":"10.1016/j.bbcan.2024.189154","title":"Reactive oxygen species of tumor microenvironment: Harnessing for immunogenic cell death","year":2024,"lang":"en","type":"review","venue":"Biochimica et Biophysica Acta (BBA) - Reviews on Cancer","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"University of Alabama","keywords":"Tumor microenvironment; Immunogenic cell death; Immune system; Immunotherapy; Cancer immunotherapy; Biology; Immunogenicity; Cancer research; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["metaepi_narrow"],"category_scores_codex":[0.000624,0.0016685,0.005086146,0.0003914025,0.0002559177,0.00008005228,0.001459041,0.000761074,0.0005440057],"category_scores_gemma":[0.00006171242,0.001245692,0.003118951,0.0005298638,0.0005748601,0.0001413118,0.0004866133,0.001441916,0.0013999],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009757995,"about_ca_system_score_gemma":0.0007760547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004877162,"about_ca_topic_score_gemma":0.000003240385,"domain_scores_codex":[0.9941565,0.0007757835,0.002199331,0.001717264,0.0001565954,0.0009944702],"domain_scores_gemma":[0.9950516,0.0004381951,0.00260971,0.001747767,0.00009175133,0.00006103658],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002564908,0.0006017499,9.09459e-8,0.06059333,0.002717733,0.000005809783,0.0003697119,2.809245e-7,0.7584374,0.0001578505,0.04247504,0.1343845],"study_design_scores_gemma":[0.0004347232,0.0002242008,0.000003532962,0.03016807,0.004318841,0.00001542109,0.00001783082,1.949012e-7,0.2311868,0.00002325118,0.7327409,0.0008662205],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001313683,0.9873798,0.000005118352,0.0001532853,0.003231053,0.004373333,0.002537312,0.00008299141,0.0009233554],"genre_scores_gemma":[0.0003687451,0.9841943,0.0002059898,0.0003195784,0.0004150002,0.002460813,0.001430448,0.000348392,0.01025678],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.6902659,"threshold_uncertainty_score":0.9996062,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06108946425850532,"score_gpt":0.3343243996057078,"score_spread":0.2732349353472024,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}