{"id":"W4400686130","doi":"10.1128/mbio.01599-24","title":"Bipotential B-neutrophil progenitors are present in human and mouse bone marrow and emerge in the periphery upon stress hematopoiesis","year":2024,"lang":"en","type":"article","venue":"mBio","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Glycomics Centre; Women and Children’s Health Research Institute; University of Alberta","funders":"Canadian Institutes of Health Research; University of Alberta","keywords":"Myelopoiesis; Haematopoiesis; Myeloid; Biology; Immunology; Lymphopoiesis; Granulocyte; Bone marrow; Progenitor cell; Neutrophil extracellular traps; Lineage (genetic); Chemokine; Inflammation; Cell biology; Gene; Stem cell; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002200437,0.0002028314,0.000257932,0.000182914,0.0001427291,0.00006664716,0.0001384144,0.0001661106,0.0001225696],"category_scores_gemma":[0.000009871775,0.0001452551,0.00004942609,0.0001847911,0.0001422788,0.000110058,0.0001332284,0.0003386009,0.00002291362],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002462595,"about_ca_system_score_gemma":0.00001497547,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002310098,"about_ca_topic_score_gemma":0.0005163092,"domain_scores_codex":[0.9987233,0.0002602233,0.0002559694,0.000397187,0.00004840193,0.0003149111],"domain_scores_gemma":[0.9996675,0.00004572345,0.00004284672,0.000207587,0.00001608566,0.00002030749],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007091295,0.0001762832,0.004134237,0.0001802613,0.00007101028,0.0002869758,0.001732142,0.000002205165,0.9894867,0.002001755,0.0007384542,0.001119045],"study_design_scores_gemma":[0.001633731,0.0003089952,0.02155257,0.0002976072,0.00007273386,0.000206714,0.004231677,0.00001781612,0.9577793,0.0008949071,0.01252083,0.0004830819],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9874646,0.01071483,0.000004853643,0.001013002,0.0002468206,0.000383197,0.00005229868,0.00004277821,0.00007761442],"genre_scores_gemma":[0.9987299,0.0002715297,0.00001244153,0.00006635152,0.00006781431,0.00008319489,0.00004046897,0.00002188823,0.0007063443],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03170739,"threshold_uncertainty_score":0.5923333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01226275159674031,"score_gpt":0.2389713117623209,"score_spread":0.2267085601655806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}