{"id":"W4400693294","doi":"10.1007/s10237-024-01868-w","title":"HepG2 cells undergo regulatory volume decrease by mechanically induced efflux of water and solutes","year":2024,"lang":"en","type":"article","venue":"Biomechanics and Modeling in Mechanobiology","topic":"Erythrocyte Function and Pathophysiology","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Saskatchewan","funders":"Gabriel Dumont Institute of Native Studies and Applied Research; Natural Sciences and Engineering Research Council of Canada","keywords":"Efflux; Volume (thermodynamics); Materials science; Biophysics; Cell biology; Chemistry; Biochemistry; Biology; Thermodynamics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000505119,0.0002366714,0.0005175146,0.0003253158,0.00005157221,0.00001352964,0.00006989622,0.0004838274,0.00007889994],"category_scores_gemma":[0.00004256615,0.0001785044,0.00007654387,0.0001434353,0.0000490048,0.00004334439,0.0001425724,0.0002581638,0.00001074703],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000407732,"about_ca_system_score_gemma":0.0001000311,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008129355,"about_ca_topic_score_gemma":0.00001415064,"domain_scores_codex":[0.9984031,0.00009643838,0.0004513395,0.0005807711,0.00009521264,0.0003731529],"domain_scores_gemma":[0.9993875,0.00007062752,0.00004286898,0.000236594,0.00006698936,0.0001953976],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00015911,0.00006861344,0.00000374079,0.000237601,0.00005842303,0.00001491299,0.0001283858,0.000007069508,0.991564,0.00525014,0.0001828476,0.002325151],"study_design_scores_gemma":[0.00119971,0.001442656,0.000002548855,0.0002310959,0.0001075678,0.0001384273,0.0001620028,0.50816,0.4687804,0.01816601,0.001311613,0.0002979505],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9749552,0.001716502,0.02149611,0.0006167146,0.0007625704,0.0003048048,0.00003059637,0.00008235285,0.00003515099],"genre_scores_gemma":[0.996392,0.001316608,0.00126857,0.0005744586,0.00007087743,0.0000219928,0.0001099543,0.00003586752,0.000209696],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5227836,"threshold_uncertainty_score":0.7279196,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02761991237326899,"score_gpt":0.2529386263524868,"score_spread":0.2253187139792178,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}