{"id":"W4400720516","doi":"10.1016/j.nbd.2024.106607","title":"Role of cell metabolism in the pathophysiology of brain size-associated neurodevelopmental disorders","year":2024,"lang":"en","type":"review","venue":"Neurobiology of Disease","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Neocortex; Neurogenesis; Cell metabolism; Biology; Microcephaly; Neuroscience; Neural stem cell; Metabolism; Progenitor cell; Stem cell; Endocrinology; Cell biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003865339,0.0007335267,0.001095668,0.001760846,0.000233912,0.0006513033,0.0007174474,0.0009011698,0.003119494],"category_scores_gemma":[0.0005455673,0.0001808002,0.0003902369,0.001691028,0.0003979801,0.0008761508,0.0006038017,0.001150902,0.001398053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005546538,"about_ca_system_score_gemma":0.0009064747,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009056299,"about_ca_topic_score_gemma":0.00149508,"domain_scores_codex":[0.9998875,0.00002272623,0.00002001797,0.00002092307,0.00003641945,0.00001236048],"domain_scores_gemma":[0.9998086,0.00009802702,0.00002436895,0.000005330356,0.00004630001,0.00001755437],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007389495,0.00004514352,0.0002981368,0.01653896,0.0001253248,0.0004262773,0.00006308213,0.0003303144,0.002084757,0.003646211,0.02504962,0.9513182],"study_design_scores_gemma":[0.00001637836,0.00007769006,0.001538876,0.003703723,0.0001839786,0.003249323,0.0000576918,0.00009534857,0.0007014373,0.002693836,0.9876615,0.00002031607],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001043188,0.9986668,0.0001283757,0.0002281286,0.0001426331,0.000003006577,0.00001689843,0.000008190967,0.0007017433],"genre_scores_gemma":[0.0005750503,0.9987077,0.0001363411,0.0001206855,0.0001077908,0.000003894051,0.00002439431,0.000001243883,0.0003229412],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003119494,"threshold_uncertainty_score":0.01043576,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0079049012722382,"score_gpt":0.2626782527712217,"score_spread":0.2547733514989835,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}