{"id":"W4400727151","doi":"10.3390/diagnostics14141545","title":"The Surviving, Not Thriving, Photoreceptors in Patients with ABCA4 Stargardt Disease","year":2024,"lang":"en","type":"article","venue":"Diagnostics","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Eye Institute; Canadian Institutes of Health Research; National Institute on Aging; National Institutes of Health","keywords":"ABCA4; Stargardt disease; Thriving; Disease; Medicine; Biology; Psychology; Ophthalmology; Internal medicine; Retinal; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000207718,0.0005189612,0.0002856099,0.001105351,0.0005731745,0.0004500482,0.0001657945,0.0005379189,0.0009422146],"category_scores_gemma":[0.0008799055,0.0001789438,0.0002029365,0.0006228859,0.0004180331,0.000357094,0.0002864482,0.0003204434,0.0001338857],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002353063,"about_ca_system_score_gemma":0.0001952198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00161554,"about_ca_topic_score_gemma":0.002112753,"domain_scores_codex":[0.9998217,0.00002153655,0.00002678529,0.00005791486,0.00004659194,0.00002548544],"domain_scores_gemma":[0.9997429,0.00005719148,0.00009778269,0.0000172495,0.00003271077,0.00005222801],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009140567,0.0001391915,0.8693213,0.0001127131,0.00007693419,0.04927673,0.0009152504,0.000254172,0.05212584,0.0002908648,0.0005672991,0.02600576],"study_design_scores_gemma":[0.00002937246,0.0006578981,0.8450888,0.00002712432,0.0000933681,0.1463342,0.0007299213,0.0006507253,0.00492203,0.0003921893,0.001055896,0.00001847054],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987968,0.000345235,0.0001765143,0.00007239438,0.00000632051,0.000009195735,0.00006681238,0.00001655682,0.0005100755],"genre_scores_gemma":[0.9994729,0.0001161232,0.0001866353,0.00003598338,0.000005894395,0.000002111906,0.00004799246,0.000002718914,0.0001297362],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00161554,"threshold_uncertainty_score":0.003212214,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002310469530325696,"score_gpt":0.1936670639186407,"score_spread":0.191356594388315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}