{"id":"W4400736375","doi":"10.1016/j.tibtech.2024.06.008","title":"Applications and evolution of 3D cancer-immune cell models","year":2024,"lang":"en","type":"review","venue":"Trends in biotechnology","topic":"Mathematical Biology Tumor Growth","field":"Mathematics","cited_by":9,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Canadian Institutes of Health Research","keywords":"Immune system; Biology; Cancer; Computational biology; Cancer cell; Chemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004938622,0.0007620723,0.001001103,0.001119851,0.0002002656,0.0009312176,0.001439737,0.001100584,0.002454611],"category_scores_gemma":[0.001017313,0.0004004238,0.0007365212,0.001188168,0.0009517763,0.001130621,0.0008612153,0.001450067,0.001139394],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001212471,"about_ca_system_score_gemma":0.0006288188,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00191012,"about_ca_topic_score_gemma":0.001757406,"domain_scores_codex":[0.9998779,0.00003348292,0.000008781977,0.00001937769,0.00005042385,0.000009919314],"domain_scores_gemma":[0.9997501,0.0001334622,0.00002619984,0.00001914782,0.00005520996,0.00001588713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005205926,0.00004567321,0.000385279,0.004247823,0.0001092443,0.000149012,0.00008884602,0.08163739,0.003096497,0.3151434,0.02023968,0.574805],"study_design_scores_gemma":[0.00002918898,0.00007114001,0.0005896277,0.001566659,0.00009199294,0.0007123957,0.00004680712,0.08371643,0.002860453,0.2052663,0.7049888,0.00006022805],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001937147,0.9484757,0.03433883,0.00174816,0.0007652331,0.0000139676,0.00009053369,0.00009054594,0.01253991],"genre_scores_gemma":[0.02563996,0.954696,0.013325,0.0003934158,0.0006174779,0.00004310273,0.0001345385,0.00003066277,0.00511987],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002454611,"threshold_uncertainty_score":0.008797169,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06857374248390534,"score_gpt":0.3726736329088255,"score_spread":0.3040998904249201,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}