{"id":"W4400742551","doi":"10.1098/rsos.231337","title":"A three-dimensional lattice-free agent-based model of intracellular ice formation and propagation and intercellular mechanics in liver tissues","year":2024,"lang":"en","type":"article","venue":"Royal Society Open Science","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cryopreservation; Intracellular; Ice crystals; Spheroid; Biological system; Mechanics; Biophysics; Materials science; Cell biology; Computer science; Chemistry; Biology; Physics; Cell culture; Embryo; Meteorology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001574139,0.00007345415,0.0001412188,0.00003200182,0.00008897302,0.00004559053,0.0001756586,0.00006385154,0.00001320321],"category_scores_gemma":[0.0001444013,0.00005714035,0.00002591686,0.0001972271,0.0003450025,0.0003300626,0.0002905276,0.0001282604,0.000001926761],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006277952,"about_ca_system_score_gemma":0.0001553245,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001313234,"about_ca_topic_score_gemma":0.00004187281,"domain_scores_codex":[0.9991293,0.00002115357,0.000169587,0.0003606348,0.0001986121,0.0001207272],"domain_scores_gemma":[0.9995623,0.00003418308,0.00003921458,0.0002087923,0.0001052411,0.00005030471],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.001600676,0.0005928751,0.00778094,0.002189411,0.00008023549,0.00003271097,0.01406298,0.004259249,0.9075632,0.01133283,0.0009175189,0.04958736],"study_design_scores_gemma":[0.0003274397,0.0001141791,0.007965273,0.000132266,0.0000218635,0.000004416929,0.000109593,0.9594899,0.0294752,0.002270636,0.00003093635,0.0000582316],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9314901,0.00149762,0.06561717,0.0007166264,0.00004303812,0.0005411973,0.000005564511,0.00001344749,0.00007526391],"genre_scores_gemma":[0.988057,0.00002125348,0.01172959,0.00009109648,0.00001099627,0.000010606,0.000005980277,0.000003559722,0.00006987923],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.9552307,"threshold_uncertainty_score":0.2330116,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03508558044357171,"score_gpt":0.2887601753342578,"score_spread":0.2536745948906861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}