{"id":"W4400742551","doi":"10.1098/rsos.231337","title":"A three-dimensional lattice-free agent-based model of intracellular ice formation and propagation and intercellular mechanics in liver tissues","year":2024,"lang":"en","type":"article","venue":"Royal Society Open Science","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Cryopreservation; Intracellular; Ice crystals; Spheroid; Biological system; Mechanics; Biophysics; Materials science; Cell biology; Computer science; Chemistry; Biology; Physics; Cell culture; Embryo; Meteorology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003826282,0.0007208126,0.0009718984,0.0006556757,0.0008854429,0.001607319,0.001875181,0.002974712,0.002827422],"category_scores_gemma":[0.001184394,0.0007610766,0.001158706,0.0006637479,0.001924771,0.001317172,0.00122661,0.001447574,0.0005400309],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001635882,"about_ca_system_score_gemma":0.001694636,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02152942,"about_ca_topic_score_gemma":0.008188665,"domain_scores_codex":[0.9997924,0.00004616813,0.00001348837,0.00004604773,0.00006463029,0.00003730589],"domain_scores_gemma":[0.9994801,0.0002043985,0.00009509612,0.00002966326,0.0000947861,0.00009597458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.00001886432,0.00002212121,0.000305945,0.00003745134,0.00001251158,0.0001217465,0.00004971391,0.970801,0.002268132,0.02522953,0.0003293723,0.0008037203],"study_design_scores_gemma":[0.00001624208,0.000009266207,0.00009417538,0.000005343275,0.000005112329,0.00001906859,0.000009857712,0.9954515,0.0001256402,0.003828686,0.0004251978,0.000009831256],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1612592,0.001788778,0.7728615,0.003584657,0.00044572,0.0001971325,0.001267485,0.0004062265,0.05818929],"genre_scores_gemma":[0.8819245,0.00185437,0.07313175,0.0007683057,0.0001667647,0.0007719644,0.000730875,0.00020053,0.04045101],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.02152942,"threshold_uncertainty_score":0.04280818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03508558044357171,"score_gpt":0.2887601753342578,"score_spread":0.2536745948906861,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}