{"id":"W4400823177","doi":"10.3390/cells13141216","title":"Graft-Specific Regulatory T Cells for Long-Lasting, Local Tolerance Induction","year":2024,"lang":"en","type":"article","venue":"Cells","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University of Toronto; University Health Network","funders":"Medizinischen Hochschule Hannover; Deutsche Forschungsgemeinschaft; Government of Canada","keywords":"Immune system; Immune tolerance; Immunology; Transplantation; Regulatory T cell; Organ transplantation; Graft rejection; Medicine; Immunity; Biology; T cell; Cancer research; IL-2 receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004340544,0.0004863126,0.0002808998,0.0003087093,0.0001474908,0.0002635671,0.000337221,0.0003107719,0.001980994],"category_scores_gemma":[0.000160126,0.00009049027,0.0002794778,0.000146424,0.0002631743,0.000197491,0.000222218,0.0009451425,0.0004745733],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001139386,"about_ca_system_score_gemma":0.0002842671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006123267,"about_ca_topic_score_gemma":0.0001682724,"domain_scores_codex":[0.9998066,0.00005226742,0.00001573816,0.00003393789,0.00005273335,0.00003882884],"domain_scores_gemma":[0.9999149,0.00001492894,0.00002255347,0.0000136986,0.00001165912,0.0000222285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000307869,0.0004368171,0.0002247789,0.0002385441,0.000008977431,0.00008594789,0.00002946341,0.0003302471,0.9746031,0.0006647406,0.0002047791,0.02286468],"study_design_scores_gemma":[0.0003729018,0.006384148,0.001443177,0.00007913145,0.0001251275,0.000823156,0.00003371764,0.00235915,0.9698174,0.0006265072,0.01792398,0.00001172762],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.894342,0.0187869,0.07639614,0.0004588831,0.0006671544,0.0007356192,0.0002573098,0.000692262,0.007663603],"genre_scores_gemma":[0.9685196,0.003763907,0.02464782,0.000230898,0.0001671837,0.000335793,0.0002342319,0.00004618074,0.002054468],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001980994,"threshold_uncertainty_score":0.006627083,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01458279599839952,"score_gpt":0.2215650503497294,"score_spread":0.2069822543513299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}