{"id":"W4400824937","doi":"10.1002/pro.5122","title":"Evidence of isochorismate channeling between the <i>Escherichia coli</i> enterobactin biosynthetic enzymes <scp>EntC</scp> and <scp>EntB</scp>","year":2024,"lang":"en","type":"article","venue":"Protein Science","topic":"Enzyme Structure and Function","field":"Materials Science","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Natural Sciences and Engineering Research Council of Canada; McMaster University","keywords":"Enterobactin; Escherichia coli; Siderophore; Chemistry; Enzyme; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001296385,0.0003183089,0.0002632915,0.0001293931,0.0001471252,0.0003344396,0.0002808494,0.0003805662,0.001017743],"category_scores_gemma":[0.0002942317,0.0001715958,0.0002489247,0.0001642412,0.0002555387,0.0002043627,0.000345671,0.0004143278,0.0002357808],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000311039,"about_ca_system_score_gemma":0.0002279809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001588345,"about_ca_topic_score_gemma":0.001220412,"domain_scores_codex":[0.9997532,0.00003924704,0.00002184231,0.00005528943,0.00008386582,0.00004662106],"domain_scores_gemma":[0.9997318,0.00006083198,0.00007979552,0.00003000382,0.00003668573,0.00006070958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000173967,0.0000450458,0.001548922,0.0000290236,0.00001076268,0.00009292131,0.00002156844,0.0001919786,0.9970354,0.0001391994,0.00002528658,0.0006858502],"study_design_scores_gemma":[0.0000111114,0.0001961514,0.01065317,0.000004371576,0.0000121789,0.0003556803,0.00006469184,0.002747845,0.985472,0.00004855598,0.000426015,0.000008085704],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981422,0.000122799,0.001148139,0.00003911338,0.000004477301,0.00000484771,0.0001209127,0.00002917652,0.0003882035],"genre_scores_gemma":[0.9988222,0.00004950746,0.0005338753,0.00001342662,7.087498e-7,0.000003534319,0.0002387084,0.000007675287,0.0003303566],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001588345,"threshold_uncertainty_score":0.003404737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02453956624213753,"score_gpt":0.2624902431332194,"score_spread":0.2379506768910818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}