{"id":"W4400840474","doi":"10.1016/j.cgh.2024.05.051","title":"IBD Matchmaking: Rational Combination Therapy","year":2024,"lang":"en","type":"review","venue":"Clinical Gastroenterology and Hepatology","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre Hospitalier de l’Université de Montréal","funders":"National Institutes of Health","keywords":"Medicine; Ulcerative colitis; Context (archaeology); Inflammatory bowel disease; Disease; Intensive care medicine; Observational study; Inflammatory Bowel Diseases; Crohn's disease; Clinical trial; Randomized controlled trial; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008366621,0.0007891835,0.002001208,0.001196853,0.0002166442,0.001465217,0.001139805,0.001193761,0.005002251],"category_scores_gemma":[0.00106501,0.0002565066,0.0007545901,0.001077421,0.0004980343,0.001078264,0.0007149418,0.003657634,0.001672853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007655764,"about_ca_system_score_gemma":0.0006966671,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007519452,"about_ca_topic_score_gemma":0.001826664,"domain_scores_codex":[0.9996868,0.00009326958,0.0000336367,0.00005164776,0.0000941215,0.0000404964],"domain_scores_gemma":[0.9996701,0.0002006758,0.00003744418,0.000009313146,0.00005102538,0.00003148128],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00024516,0.0001381911,0.0001501836,0.006641118,0.000175726,0.0002052822,0.00002737466,0.0008066439,0.0006565403,0.004898902,0.0413618,0.9446931],"study_design_scores_gemma":[0.0002851215,0.0002716531,0.0006638729,0.004734359,0.0003588326,0.001748523,0.00005406289,0.0005341638,0.0004971536,0.007273688,0.9835418,0.00003688833],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001689716,0.9967662,0.0005414144,0.0006607175,0.0003444989,0.00001189845,0.00002790863,0.00001578196,0.001462658],"genre_scores_gemma":[0.002525574,0.9940983,0.0009744007,0.0009398145,0.000435517,0.00002742782,0.00008579784,0.000005187405,0.0009081187],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005002251,"threshold_uncertainty_score":0.01673424,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05979672707696427,"score_gpt":0.3902632656695423,"score_spread":0.330466538592578,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}