{"id":"W4400858449","doi":"10.1016/j.oret.2024.07.012","title":"Effect of Brolucizumab and Aflibercept on the Maximum Thickness of Pigment Epithelial Detachments and Sub-Retinal Pigment Epithelium Fluid in HAWK and HARRIER","year":2024,"lang":"en","type":"article","venue":"Ophthalmology Retina","topic":"Retinal Diseases and Treatments","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; St. Michael's Hospital","funders":"","keywords":"Aflibercept; Ophthalmology; Medicine; Pigment; Optometry; Surgery; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000655089,0.0002952697,0.0005779544,0.0001452012,0.00006509112,0.00001904767,0.00007625914,0.0001460865,0.0001296448],"category_scores_gemma":[0.00009526469,0.0001799382,0.00009494137,0.0001376157,0.0005066196,0.00004205681,0.000127204,0.0002222362,0.000008124928],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004772935,"about_ca_system_score_gemma":0.00004739255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008539946,"about_ca_topic_score_gemma":9.814888e-7,"domain_scores_codex":[0.9981822,0.0003762647,0.0003835549,0.0004897381,0.0002710878,0.0002971374],"domain_scores_gemma":[0.9989253,0.0005082667,0.00009836656,0.0002888397,0.00003603408,0.0001431382],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0153013,0.0008652767,0.8944972,0.003878507,0.0007524851,0.004277678,0.001431796,0.000002803186,0.05211663,0.001078809,0.0001345691,0.02566292],"study_design_scores_gemma":[0.0045489,0.01195404,0.9398458,0.001792049,0.0007507571,0.004795962,0.0001697662,0.000205697,0.03464122,0.0009072109,0.0001281627,0.0002604553],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9927434,0.00387224,0.000002585143,0.0008896032,0.0001361745,0.0008933585,0.00006421489,0.0000126099,0.001385794],"genre_scores_gemma":[0.9990309,0.0004851072,0.00004433169,0.00004616323,0.00003268646,0.00008262785,0.00001660016,0.0000284921,0.0002330536],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04534855,"threshold_uncertainty_score":0.7337667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009151651416635044,"score_gpt":0.2871257607689633,"score_spread":0.2779741093523282,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}