{"id":"W4400882573","doi":"10.1016/j.jacadv.2024.101123","title":"Comprehensive Geriatric Assessment to Optimize the Management of Older Patients With Transthyretin Cardiac Amyloidosis","year":2024,"lang":"en","type":"review","venue":"JACC Advances","topic":"Amyloidosis: Diagnosis, Treatment, Outcomes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Libin Cardiovascular Institute of Alberta","funders":"Ministero della Salute; British Heart Foundation; National Institutes of Health; Prothena; Novo Nordisk; Cytokinetics; American Heart Association; Sanofi; Alnylam Pharmaceuticals; Pfizer; AstraZeneca","keywords":"Medicine; Quality of life (healthcare); Mood; Amyloidosis; Transthyretin; Disease; Cognition; Intensive care medicine; Gerontology; Psychiatry; Internal medicine; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009243737,0.0007059193,0.001305234,0.001461333,0.0001786758,0.0009608782,0.0006020522,0.0007396054,0.002125513],"category_scores_gemma":[0.002150076,0.0001342209,0.0009338271,0.0009857345,0.000165062,0.0007039574,0.0006032495,0.001368503,0.0008756354],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004555988,"about_ca_system_score_gemma":0.00126072,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001250477,"about_ca_topic_score_gemma":0.002486137,"domain_scores_codex":[0.9996427,0.0001043879,0.00007740183,0.00003338193,0.0001128736,0.00002920614],"domain_scores_gemma":[0.9994649,0.000243716,0.00007716903,0.00001070648,0.0001694328,0.00003398212],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001037664,0.00007388629,0.0007671886,0.0188433,0.0003758527,0.0001911412,0.00007153831,0.0002994054,0.0005944027,0.001236696,0.02813187,0.949311],"study_design_scores_gemma":[0.0001365016,0.0003400602,0.008894059,0.03998727,0.001728718,0.003113383,0.0002345682,0.0004770639,0.0006935121,0.004199633,0.9401385,0.00005678111],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003349444,0.9975224,0.0002469178,0.0006925811,0.0002190686,0.00001375988,0.0000553881,0.00001268323,0.0009022199],"genre_scores_gemma":[0.002769853,0.9953663,0.0006496037,0.0004758908,0.0002762273,0.00002448586,0.000115478,0.00000306795,0.0003190851],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002125513,"threshold_uncertainty_score":0.007110536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0116069001903729,"score_gpt":0.3201265950810459,"score_spread":0.3085196948906729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}