{"id":"W4400902769","doi":"10.1111/epi.18063","title":"WONOEP appraisal: Modeling early onset epilepsies","year":2024,"lang":"en","type":"review","venue":"Epilepsia","topic":"Neuroscience and Neuropharmacology Research","field":"Neuroscience","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Krembil Foundation; University of Toronto","funders":"Medical Research Future Fund; UCB Pharma; National Institute of Neurological Disorders and Stroke; National Health and Medical Research Council; Intellectual and Developmental Disabilities Research Center; Montpellier Université d'Excellence; Epilepsy Society; Jazz Pharmaceuticals; Eisai; University of Toronto; National Institutes of Health; Canada First Research Excellence Fund; Agence Nationale de la Recherche; Science Foundation Ireland; LivaNova; Mitacs; SK Life Science; Ontario Centres of Excellence; Eunice Kennedy Shriver National Institute of Child Health and Human Development; U.S. Department of Defense","keywords":"Epilepsy; Epileptogenesis; Neuroscience; Zebrafish; Psychology; Medicine; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0037867,0.001461559,0.001004896,0.001705263,0.0005971239,0.002640267,0.002285088,0.00231938,0.03960088],"category_scores_gemma":[0.006906291,0.000509824,0.001568784,0.001309619,0.0005179442,0.00223675,0.002600526,0.002352069,0.01002829],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0015513,"about_ca_system_score_gemma":0.003523673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003844201,"about_ca_topic_score_gemma":0.007026568,"domain_scores_codex":[0.9984117,0.0003314883,0.00009252431,0.0001100079,0.0008613681,0.0001930094],"domain_scores_gemma":[0.9963731,0.0008683969,0.0002248436,0.000149316,0.001883169,0.0005012431],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0003791414,0.0001118359,0.0007314398,0.01057823,0.0002343762,0.0005906713,0.0002618836,0.007021553,0.01256855,0.02902276,0.6496797,0.2888198],"study_design_scores_gemma":[0.00006953436,0.0002007571,0.0005588673,0.002848339,0.0001188588,0.0001976002,0.00008776145,0.002515083,0.002540914,0.006766089,0.9840636,0.00003252353],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"other","genre_gemma":"review","genre_scores_codex":[0.01444619,0.3072115,0.1986452,0.0696497,0.06774201,0.004307856,0.01816184,0.007727033,0.3121088],"genre_scores_gemma":[0.08122875,0.5049595,0.1245218,0.02088679,0.01904425,0.004932225,0.02840176,0.005655377,0.2103696],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.03960088,"threshold_uncertainty_score":0.1324781,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2084359646475873,"score_gpt":0.4598381388245371,"score_spread":0.2514021741769498,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}