{"id":"W4400903047","doi":"10.1186/s13041-024-01115-4","title":"The myelin water imaging transcriptome: myelin water fraction regionally varies with oligodendrocyte-specific gene expression","year":2024,"lang":"en","type":"article","venue":"Molecular Brain","topic":"Advanced Neuroimaging Techniques and Applications","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; International Collaboration On Repair Discoveries; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; Michael Smith Health Research BC; BC Children's Hospital; International Foundation for Research in Paraplegia; Craig H. Neilsen Foundation; National Science Foundation","keywords":"Myelin; Brain atlas; Neuroimaging; Gene expression; Biology; Transcriptome; Human brain; Neuroscience; Gene; Computational biology; Genetics; Central nervous system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002111932,0.0002142514,0.0001654334,0.00009899391,0.000286435,0.0001472405,0.0001466973,0.00005358435,0.00005052699],"category_scores_gemma":[0.000008936272,0.0001072185,0.0001083698,0.0001261281,0.000140962,0.0001350421,0.00004764913,0.0003673907,0.00006764047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007288105,"about_ca_system_score_gemma":0.00002754308,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000006468236,"about_ca_topic_score_gemma":9.24571e-7,"domain_scores_codex":[0.9985329,0.00005364606,0.0002405975,0.0004818424,0.0003236403,0.0003674118],"domain_scores_gemma":[0.9992337,0.00005289715,0.00002172209,0.0005286554,0.00007595147,0.00008706336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000994904,0.00002835527,0.00002071611,0.00003046346,0.00001981252,0.0003334851,0.000252376,0.00004585033,0.9877688,0.0009465545,0.006496336,0.003957709],"study_design_scores_gemma":[0.0002259281,0.0000326125,0.00004683831,0.0001075502,0.00002743715,0.0002824805,0.00003353163,0.0004928699,0.6982664,0.002161136,0.2981964,0.0001268128],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"methods","genre_gemma":"empirical","genre_scores_codex":[0.1469009,0.002020599,0.7784946,0.07068437,0.0001132138,0.000618823,0.000007463994,0.0006669709,0.0004930753],"genre_scores_gemma":[0.9782977,0.0002739162,0.01686329,0.002520611,0.0001888509,0.0002309619,0.0001510407,0.000108977,0.001364665],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.8313968,"threshold_uncertainty_score":0.4372244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02123735456096942,"score_gpt":0.2884411997218314,"score_spread":0.2672038451608619,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}