{"id":"W4400952744","doi":"10.1161/atvb.44.suppl_1.1056","title":"Abstract 1056: Overexpression Of Lysosomal Acid Lipase","year":2024,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Calcium signaling and nucleotide metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Lipase; Lysosome; Chemistry; Biology; Biochemistry; Internal medicine; Cell biology; Endocrinology; Enzyme; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003936542,0.0007092803,0.0005385954,0.0003895764,0.0002473788,0.0006457837,0.0003082725,0.0007313225,0.004437943],"category_scores_gemma":[0.0001995426,0.0002892863,0.0006682217,0.0005265343,0.0002795066,0.0002926116,0.0003822341,0.0008477567,0.003550469],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005446616,"about_ca_system_score_gemma":0.0003858268,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005945162,"about_ca_topic_score_gemma":0.0004346962,"domain_scores_codex":[0.9994836,0.00006916909,0.0001095143,0.00009542305,0.0001446254,0.00009761944],"domain_scores_gemma":[0.9997246,0.00004014635,0.00006946014,0.00004788156,0.00004528297,0.00007264374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002152964,0.00006375246,0.0001337391,0.00009332557,0.00001070895,0.0001005137,0.00001197108,0.00005880416,0.9980838,0.0001080765,0.0002020168,0.000917832],"study_design_scores_gemma":[0.00005266035,0.0004393272,0.0009244428,0.00001311395,0.00003476215,0.000389045,0.00001516731,0.00069517,0.9900484,0.00003764858,0.007342512,0.000007709601],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9636004,0.00475886,0.01262808,0.0007972039,0.0004996647,0.0002226303,0.007790163,0.001193852,0.008509137],"genre_scores_gemma":[0.9474148,0.002891686,0.01309478,0.0002013596,0.0001372667,0.0002545817,0.0119157,0.0002004027,0.02388946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004437943,"threshold_uncertainty_score":0.01484644,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02296136124218756,"score_gpt":0.2826245977573256,"score_spread":0.2596632365151381,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}