{"id":"W4400952784","doi":"10.1161/atvb.44.suppl_1.3066","title":"Abstract 3066: Pro-Atherogenic Macrophages Induce The Upregulation Of MLKL And Cell Death In Vascular Smooth Muscle Cells During Atherogenic Stimulation","year":2024,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Atherosclerosis and Cardiovascular Diseases","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ottawa Heart Institute; University of Ottawa","funders":"","keywords":"Downregulation and upregulation; Stimulation; Vascular smooth muscle; Programmed cell death; Cell biology; Medicine; Inflammation; Chemistry; Cancer research; Smooth muscle; Internal medicine; Endocrinology; Apoptosis; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001710273,0.0004076475,0.0003374987,0.0002282262,0.0001591269,0.0002127037,0.0002072247,0.0004035188,0.004418278],"category_scores_gemma":[0.0001046897,0.0001485593,0.0003397674,0.0001902803,0.0002496787,0.0002142762,0.0002418786,0.0008559206,0.001514601],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002127104,"about_ca_system_score_gemma":0.0001690894,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001701657,"about_ca_topic_score_gemma":0.0002209389,"domain_scores_codex":[0.9997637,0.00003502959,0.00002921377,0.00003473684,0.00006696947,0.0000704476],"domain_scores_gemma":[0.9998589,0.00001908067,0.00003391042,0.00002026727,0.00002299458,0.00004475723],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004002287,0.00004592357,0.0001875204,0.00007277943,0.000003727112,0.00008110613,0.00001004484,0.00001873894,0.9985563,0.0000435384,0.00008177702,0.000498349],"study_design_scores_gemma":[0.00007346041,0.0007037076,0.008243036,0.00001498117,0.00001355084,0.0004922855,0.00003371824,0.0002642516,0.9880109,0.00005789677,0.00208783,0.000004327326],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9897261,0.002447708,0.002407823,0.0003752351,0.0001243562,0.00008774752,0.001786224,0.0001202244,0.002924549],"genre_scores_gemma":[0.9823318,0.001352179,0.003403641,0.0002914544,0.0000800679,0.0001893244,0.003541789,0.00002562242,0.008784134],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004418278,"threshold_uncertainty_score":0.01478064,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02135827563658774,"score_gpt":0.247055125144162,"score_spread":0.2256968495075743,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}