{"id":"W4400952981","doi":"10.1161/atvb.44.suppl_1.1133","title":"Abstract 1133: Docosahexaenoic Acid’s Impact On The HMG CoA Reductase Pathway: Endothelial Cell Growth State-dependency And Implications For Cardiovascular Health","year":2024,"lang":"en","type":"article","venue":"Arteriosclerosis Thrombosis and Vascular Biology","topic":"Eicosanoids and Hypertension Pharmacology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"HMG-CoA reductase; Docosahexaenoic acid; Reductase; Dependency (UML); Endothelial stem cell; Cell growth; Cell biology; Biochemistry; Biology; Enzyme; Chemistry; Medicine; Internal medicine; Endocrinology; Fatty acid; Computer science; Polyunsaturated fatty acid","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004686045,0.0007496714,0.001078538,0.0007960913,0.0007706577,0.001424278,0.0003390415,0.0005497891,0.00651108],"category_scores_gemma":[0.0006145095,0.0003214022,0.001150578,0.002091505,0.0002329134,0.0006536368,0.0007940219,0.001048767,0.002304273],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006911508,"about_ca_system_score_gemma":0.001283757,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003317276,"about_ca_topic_score_gemma":0.003387109,"domain_scores_codex":[0.9996644,0.00002987027,0.00002402757,0.0001166301,0.000110582,0.00005436288],"domain_scores_gemma":[0.9996934,0.00006430114,0.00005873262,0.00002033467,0.0001167572,0.00004650583],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003686205,0.000099107,0.01931609,0.004760113,0.0004348822,0.0006369589,0.0003878745,0.001305728,0.8834386,0.001897939,0.01896521,0.06507143],"study_design_scores_gemma":[0.0003350566,0.001064984,0.3587582,0.001586749,0.002342301,0.002582247,0.0008500332,0.01330226,0.4128515,0.005677596,0.2003529,0.0002959748],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.5794921,0.08067849,0.03205677,0.004273126,0.002967825,0.0003420472,0.2800541,0.002407572,0.01772793],"genre_scores_gemma":[0.5906543,0.03915676,0.02825153,0.002785852,0.000553057,0.0004502917,0.312059,0.001098215,0.02499087],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00651108,"threshold_uncertainty_score":0.0217818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03530651688343053,"score_gpt":0.307992285631797,"score_spread":0.2726857687483665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}