{"id":"W4400959687","doi":"10.1242/jeb.247642","title":"The role of the heart in the evolution of aerobic performance","year":2024,"lang":"en","type":"article","venue":"Journal of Experimental Biology","topic":"High Altitude and Hypoxia","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia, Okanagan Campus; University of British Columbia; McMaster University","funders":"Killam Trusts; Natural Sciences and Engineering Research Council of Canada; University of British Columbia; Canada Research Chairs; McMaster University","keywords":"Effects of high altitude on humans; Aerobic capacity; Cardiac output; Oxygen transport; Biology; Acclimatization; Internal medicine; Blood viscosity; Diffusing capacity; Skeletal muscle; Endocrinology; Chemistry; Oxygen; Anatomy; Blood pressure; Ecology; Lung; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003062867,0.00005296578,0.00008835202,0.0000236314,0.00004366122,0.000005746089,0.0002563476,0.0000579115,0.000005851522],"category_scores_gemma":[0.00001443361,0.0000230925,0.0001022096,0.00007412796,0.0001540582,0.000003740543,0.00005186813,0.0001036809,0.000001279009],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000193889,"about_ca_system_score_gemma":0.00007391954,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001633567,"about_ca_topic_score_gemma":0.00001220697,"domain_scores_codex":[0.9994429,0.0001008438,0.0002379474,0.00006071674,0.0000659782,0.00009157322],"domain_scores_gemma":[0.9997106,0.00002411542,0.00009304632,0.0001329043,0.00002856613,0.00001080986],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005074588,0.00003827321,0.005624105,0.000003153292,0.00002344441,3.040992e-7,0.000200701,0.00000596237,0.992579,0.0009260196,0.0003360762,0.0002121989],"study_design_scores_gemma":[0.0001429034,0.0005998202,0.00462327,0.00002234491,0.000006640961,0.00007657188,0.00112035,0.00002303833,0.9600673,0.000105542,0.03318239,0.0000298657],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.96415,0.03485343,0.000004837183,0.0002669076,0.0002454571,0.00005695622,0.00000185627,5.356674e-7,0.0004200022],"genre_scores_gemma":[0.9995059,0.0002492497,0.00002780887,0.00006261459,0.0001201962,0.000002764202,0.000001048945,0.000003316555,0.00002707202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03535591,"threshold_uncertainty_score":0.0941685,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006082156561099405,"score_gpt":0.2612038825799765,"score_spread":0.2551217260188771,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}