{"id":"W4400968083","doi":"10.1093/cid/ciae386","title":"US Food and Drug Administration, Centers for Disease Control and Prevention, and National Institutes of Health Co-Sponsored Public Workshop Summary—Development Considerations of Antimicrobial Drugs for the Treatment of Gonorrhea","year":2024,"lang":"en","type":"article","venue":"Clinical Infectious Diseases","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Center for Drug Evaluation and Research; National Institute of Allergy and Infectious Diseases; Uniformed Services University of the Health Sciences; Nabriva Therapeutics; Biomedical Advanced Research and Development Authority; Centers for Disease Control and Prevention; Public Health Agency; Novo Nordisk; Public Health Agency of Canada; Bundesministerium für Bildung und Forschung; Wellcome Trust; American Sexually Transmitted Diseases Association; Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator; Gilead Sciences; GlaxoSmithKline; U.S. Food and Drug Administration; Moderna; Henry M. Jackson Foundation; Department of Health and Social Care; National Institutes of Health; Administration for Strategic Preparedness and Response; U.S. Department of Health and Human Services; Bundesministerium für Bildung und Frauen; Louisiana State University; Bill and Melinda Gates Foundation","keywords":"Medicine; Food and drug administration; Disease control; Gonorrhea; Drug; Public health; Antimicrobial; Drug development; Family medicine; Intensive care medicine; Environmental health; Pharmacology; Nursing; Human immunodeficiency virus (HIV); Microbiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01844958,0.001848643,0.0008116915,0.001479395,0.002349102,0.00524851,0.002541024,0.01262875,0.03675006],"category_scores_gemma":[0.009550415,0.0005994479,0.001142317,0.001008083,0.001115353,0.002097588,0.003628694,0.0110645,0.009496104],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004089749,"about_ca_system_score_gemma":0.02335567,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01193677,"about_ca_topic_score_gemma":0.02049082,"domain_scores_codex":[0.9914336,0.002528183,0.0004566138,0.0004719787,0.003293678,0.001815961],"domain_scores_gemma":[0.9838364,0.002423214,0.001135368,0.0005476082,0.007760661,0.00429673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001314269,0.0002524401,0.0006102597,0.000195474,0.00002283073,0.0001576804,0.0000394072,0.0001139067,0.0008188617,0.001607802,0.963236,0.03281384],"study_design_scores_gemma":[0.00009966506,0.0001974458,0.001961163,0.000427251,0.00002232466,0.00009090328,0.0002053552,0.0001638475,0.0005712563,0.0006677666,0.9955537,0.00003945687],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"other","genre_scores_codex":[0.003446416,0.02466193,0.003909091,0.7493687,0.04805969,0.002911252,0.004565203,0.0005027888,0.1625749],"genre_scores_gemma":[0.04863346,0.04348314,0.01773659,0.5020567,0.02945057,0.00408589,0.01250698,0.000309857,0.3417368],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.03675006,"threshold_uncertainty_score":0.1229411,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06321796405303816,"score_gpt":0.396241950349306,"score_spread":0.3330239862962679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}