{"id":"W4400981524","doi":"10.1165/rcmb.2024-0089oc","title":"MicroRNA-155-5p Differentially Regulates IL-13Rα1 and IL-13Rα2 Expression and Signaling Driving Abnormal Lung Epithelial Cell Phenotype in Severe Asthma","year":2024,"lang":"en","type":"article","venue":"American Journal of Respiratory Cell and Molecular Biology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval; Institut universitaire de cardiologie et de pneumologie de Québec","funders":"Canadian Institutes of Health Research","keywords":"Western blot; Interleukin 13; Transfection; Signal transduction; Stimulation; Blot; Biology; Medicine; Immunology; Cell biology; Cancer research; Immune system; Interleukin 4; Cell culture; Endocrinology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001853775,0.0001931741,0.0003698424,0.0002000676,0.0001580615,0.0003160917,0.0000900516,0.0002578684,0.001085512],"category_scores_gemma":[0.0001897616,0.0002093026,0.0003672141,0.0001158309,0.0002120121,0.00009859155,0.000191527,0.000362356,0.0004268938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002171391,"about_ca_system_score_gemma":0.000142614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000258778,"about_ca_topic_score_gemma":0.0003718694,"domain_scores_codex":[0.9997833,0.00004405186,0.00002288695,0.00005421888,0.00004566197,0.00004988046],"domain_scores_gemma":[0.9999306,0.00001116141,0.00002064615,0.000006978306,0.000008471918,0.00002217282],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003972461,0.00002242921,0.001797514,0.0000383322,0.00001107166,0.0001089897,0.00002277045,0.00003276595,0.9966883,0.00004359247,0.00006039675,0.0007766066],"study_design_scores_gemma":[0.0001347766,0.001351511,0.2326978,0.00004261901,0.0001293266,0.002102411,0.0003093965,0.002610289,0.755457,0.0001421224,0.005004347,0.00001825913],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970293,0.001058746,0.0008156927,0.00005443547,0.00003226807,0.00002614075,0.0003301756,0.00002957591,0.0006235974],"genre_scores_gemma":[0.9978027,0.0002854675,0.0007662944,0.00007824711,0.000007779186,0.0000418058,0.0004170765,0.000009825648,0.0005907597],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001085512,"threshold_uncertainty_score":0.003631413,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003846777000626344,"score_gpt":0.2166850826624069,"score_spread":0.2128383056617806,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}