{"id":"W4401005664","doi":"10.1093/mam/ozae044.477","title":"Revealing the Ultrastructure and Intracellular Distributions of Secretory Granules in Malignant Human Mast Cells by Volume Electron Microscopy","year":2024,"lang":"en","type":"article","venue":"Microscopy and Microanalysis","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Alberta; National Research Council Canada; National Institute for Nanotechnology","funders":"","keywords":"Ultrastructure; Intracellular; Electron microscope; Cell biology; Chemistry; Pathology; Biophysics; Biology; Medicine; Physics; Optics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003919181,0.0003033048,0.0005109573,0.0002020595,0.0003716448,0.0000889512,0.0002037829,0.0002590305,0.0003553163],"category_scores_gemma":[0.000008416355,0.0002300822,0.0001425516,0.0003806807,0.0007006878,0.00007304973,0.00008158175,0.0004891488,0.00001505977],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000531687,"about_ca_system_score_gemma":0.00004081134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008917236,"about_ca_topic_score_gemma":0.0003462019,"domain_scores_codex":[0.9982401,0.000176052,0.000538873,0.0005448154,0.00004079444,0.000459386],"domain_scores_gemma":[0.999423,0.00008034777,0.0001277561,0.0002893598,0.00004242569,0.00003706789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003534516,0.00005089876,0.002278498,0.0001630576,0.0002409187,0.000006732264,0.0006455276,0.000002592617,0.9904717,0.0002740783,0.005328452,0.0005021779],"study_design_scores_gemma":[0.0003801854,0.00007916262,0.0009469665,0.0001242085,0.0003770291,0.00004411956,0.0003195062,0.00001668421,0.9492471,0.0001081307,0.04811959,0.0002373008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9097623,0.08776163,0.00107001,0.0002566383,0.000147899,0.0001975671,0.0007317063,0.00002735771,0.00004488709],"genre_scores_gemma":[0.9929463,0.002126208,0.0001625159,0.00004395496,0.00002276447,0.00001198451,0.000772071,0.00002494859,0.003889232],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.08563542,"threshold_uncertainty_score":0.9382477,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003568298658246657,"score_gpt":0.2257665500823416,"score_spread":0.222198251424095,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}