{"id":"W4401022200","doi":"10.1001/jama.2024.13386","title":"FDA Greenlights Second Alzheimer Drug, Donanemab","year":2024,"lang":"en","type":"article","venue":"JAMA","topic":"Pharmaceutical Economics and Policy","field":"Economics, Econometrics and Finance","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Art history; Humanities; Art; Philosophy","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007806988,0.0004894578,0.0006226687,0.0006005676,0.0006891983,0.001382649,0.0004950251,0.001647176,0.03643011],"category_scores_gemma":[0.001387072,0.0001484934,0.0005579383,0.0003989021,0.0003694684,0.0007789332,0.0004564853,0.002348002,0.01220802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009693626,"about_ca_system_score_gemma":0.001730725,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00136366,"about_ca_topic_score_gemma":0.005410884,"domain_scores_codex":[0.9994597,0.0001109917,0.0000245817,0.00008443039,0.0002368747,0.00008347022],"domain_scores_gemma":[0.9993702,0.0001123103,0.00006806037,0.00003190294,0.000210323,0.0002073187],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001590644,0.0002073883,0.0008691993,0.0003222946,0.00005534657,0.0003858104,0.00002992739,0.00008855455,0.002985758,0.003064794,0.70642,0.2839803],"study_design_scores_gemma":[0.001594499,0.0005853275,0.002274179,0.0002615335,0.0000760616,0.00130932,0.00003327683,0.000258688,0.002074778,0.001459659,0.9900542,0.00001838333],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"other","genre_gemma":"commentary","genre_scores_codex":[0.03509795,0.2224925,0.004130606,0.158107,0.02453838,0.0006310299,0.009002931,0.002505018,0.5434945],"genre_scores_gemma":[0.18974,0.1192212,0.006681129,0.06386565,0.008202911,0.0006173406,0.008952146,0.0003563566,0.6023632],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.03643011,"threshold_uncertainty_score":0.1218708,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0567950418278665,"score_gpt":0.2863818921707187,"score_spread":0.2295868503428522,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}