{"id":"W4401026662","doi":"10.1016/j.cellsig.2024.111321","title":"Inflammatory gene regulation by Cdc42 in airway epithelial cells","year":2024,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Cell biology; CDC42; Gene knockdown; Biology; Cytokine; Gene expression; Regulation of gene expression; Secretion; Golgi apparatus; Small interfering RNA; Signal transduction; Immunology; Transfection; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002788498,0.0001658782,0.0001172241,0.00008484909,0.00005475809,0.00005481648,0.0001459222,0.0001867134,0.00007916733],"category_scores_gemma":[0.00001041662,0.0001753296,0.000105478,0.0001194595,0.00004194415,0.000009969698,0.00004953238,0.0001221803,0.00008758547],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002172426,"about_ca_system_score_gemma":0.00006742553,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008261885,"about_ca_topic_score_gemma":0.000006518068,"domain_scores_codex":[0.9989162,0.00005604227,0.0002793701,0.0003557103,0.0001230774,0.0002695656],"domain_scores_gemma":[0.9996786,0.00001076528,0.00003820224,0.0002009808,0.00003005302,0.00004139417],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002685771,0.00001781144,0.0000615387,0.00004134296,0.00002677202,0.00001480655,0.0001191402,0.001605787,0.9948355,0.00005663498,0.001151799,0.002042027],"study_design_scores_gemma":[0.0002390341,0.00005075456,0.00001875396,0.00003321671,0.00001037763,0.000001491985,0.00004229513,0.002474904,0.9223058,0.0001148791,0.07449861,0.000209893],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9715217,0.01013288,0.01693193,0.00004942237,0.0003841041,0.0001702992,0.00001159708,0.00003212519,0.0007658977],"genre_scores_gemma":[0.9967182,0.0003719069,0.0001668242,0.00006164177,0.0002626548,0.00001725401,0.0003501936,0.00004244929,0.00200885],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07334681,"threshold_uncertainty_score":0.7149734,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0041477813595489,"score_gpt":0.1943747522527712,"score_spread":0.1902269708932223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}