{"id":"W4401026662","doi":"10.1016/j.cellsig.2024.111321","title":"Inflammatory gene regulation by Cdc42 in airway epithelial cells","year":2024,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Cell biology; CDC42; Gene knockdown; Biology; Cytokine; Gene expression; Regulation of gene expression; Secretion; Golgi apparatus; Small interfering RNA; Signal transduction; Immunology; Transfection; Gene; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000118076,0.0002508223,0.0002596311,0.0002652465,0.0004030975,0.0004470575,0.0001688869,0.0003710018,0.002259557],"category_scores_gemma":[0.0001703537,0.0001194587,0.0003274226,0.0002377393,0.0001578448,0.000206501,0.0003146437,0.0006962403,0.0008780776],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003206888,"about_ca_system_score_gemma":0.0003498741,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008335614,"about_ca_topic_score_gemma":0.001332368,"domain_scores_codex":[0.9997943,0.00001842704,0.00001900462,0.00004522234,0.0000918698,0.00003125543],"domain_scores_gemma":[0.9998655,0.00001459842,0.00003452583,0.0000126402,0.00004536132,0.00002728393],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004861884,0.000007775774,0.0003120582,0.00007191939,0.000002100826,0.00007604393,0.00003024227,0.00003147609,0.9970291,0.0002095641,0.0002115063,0.001969512],"study_design_scores_gemma":[0.00001454409,0.00008267879,0.01565267,0.00003481858,0.00001777893,0.0004199284,0.0001470386,0.001100533,0.9546696,0.0001837704,0.02766471,0.00001203129],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9589792,0.01068971,0.01280876,0.001464802,0.0005531975,0.0001596614,0.004803637,0.0003197325,0.01022138],"genre_scores_gemma":[0.957053,0.005530681,0.01386471,0.0006734841,0.0001202135,0.0002580922,0.004439115,0.0001550351,0.01790555],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002259557,"threshold_uncertainty_score":0.007558942,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0041477813595489,"score_gpt":0.1943747522527712,"score_spread":0.1902269708932223,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}