{"id":"W4401040770","doi":"10.17615/dg4r-3n36","title":"Genomics-Driven Precision Medicine for Advanced Pancreatic Cancer: Early Results from the COMPASS Trial","year":2024,"lang":"en","type":"article","venue":"UNC Libraries","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Cancer Institute; Canadian Cancer Society Research Institute; Hebrew University of Jerusalem; Government of Ontario","keywords":"Compass; Precision medicine; Pancreatic cancer; Medicine; Cancer; Genomics; Computational biology; Medical physics; Internal medicine; Oncology; Biology; Cartography; Pathology; Geography; Genetics; Genome; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001774798,0.0005668287,0.0005524339,0.0001719602,0.0001279574,0.0007895484,0.0001908341,0.0003350552,0.002079722],"category_scores_gemma":[0.001451351,0.00007383012,0.0005215502,0.0003323925,0.0004520314,0.0003258,0.0003587332,0.0006160834,0.0002044451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008551376,"about_ca_system_score_gemma":0.0009355431,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006719176,"about_ca_topic_score_gemma":0.001359018,"domain_scores_codex":[0.999373,0.0004105447,0.00001414468,0.00006948632,0.00007870506,0.00005399089],"domain_scores_gemma":[0.9993626,0.0001919201,0.0001442899,0.00005411668,0.00006075978,0.0001863465],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.434509,0.003621367,0.09305453,0.001535698,0.005084247,0.0004892198,0.0003379184,0.005544817,0.02209875,0.002958614,0.01669144,0.4140743],"study_design_scores_gemma":[0.2689392,0.1651396,0.4077694,0.001297703,0.008495923,0.002087162,0.0007239007,0.008287855,0.02476287,0.007177223,0.1051195,0.000199637],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9688774,0.01947843,0.001183926,0.005015341,0.0002579679,0.0001927813,0.001066866,0.00007239461,0.003854747],"genre_scores_gemma":[0.9862201,0.005380551,0.001827864,0.00257734,0.0004494095,0.0001755155,0.001756151,0.0000219944,0.001591007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002079722,"threshold_uncertainty_score":0.009386182,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01983972766753048,"score_gpt":0.2680449683314319,"score_spread":0.2482052406639015,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}