{"id":"W4401051559","doi":"10.1186/s12890-024-03167-7","title":"The effect of the mechanodynamic lung environment on fibroblast phenotype via the Flexcell","year":2024,"lang":"en","type":"review","venue":"BMC Pulmonary Medicine","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"St. Paul's Hospital; Okanagan University College; University of British Columbia, Okanagan Campus; University of British Columbia","funders":"Natural Sciences and Engineering Research Council of Canada; Mitacs; Canada Foundation for Innovation; Providence Health Care","keywords":"ARDS; Lung; Medicine; Idiopathic pulmonary fibrosis; Fibroblast; Fibrosis; Extracellular matrix; Pathology; Bronchopulmonary dysplasia; Pulmonary fibrosis; Cell biology; Cell culture; Biology; Internal medicine; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000370046,0.0008465492,0.00103401,0.002084684,0.0002317483,0.0008872557,0.0006363116,0.0009290428,0.002593451],"category_scores_gemma":[0.000372504,0.0002439926,0.0004664242,0.001552307,0.0003255227,0.000885934,0.00053453,0.001122007,0.002102958],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004744441,"about_ca_system_score_gemma":0.0005729404,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009208219,"about_ca_topic_score_gemma":0.001397127,"domain_scores_codex":[0.9998556,0.00001939906,0.00001802757,0.00003294238,0.00005849947,0.00001553548],"domain_scores_gemma":[0.9998528,0.00006671363,0.00001946687,0.000005423389,0.00004278872,0.00001278768],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001064622,0.00009043889,0.0002486923,0.02052823,0.00008935302,0.0002943978,0.00008969753,0.0004511419,0.02056396,0.003905885,0.01315314,0.9404786],"study_design_scores_gemma":[0.00001536177,0.000314727,0.001806113,0.00252094,0.0001594649,0.001842065,0.00006497937,0.0001333735,0.008454405,0.001177737,0.9834688,0.0000421211],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0003839137,0.9970394,0.0002965233,0.0001259525,0.0001467873,0.000008286846,0.00004224098,0.00001304407,0.001943886],"genre_scores_gemma":[0.001898926,0.9957227,0.0003987525,0.0001505411,0.00008253413,0.00001555548,0.00007215318,0.000004042024,0.00165492],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002593451,"threshold_uncertainty_score":0.008675992,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01018601805232303,"score_gpt":0.2753531449771682,"score_spread":0.2651671269248451,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}