{"id":"W4401075678","doi":"10.1016/j.micinf.2024.105399","title":"miR-190 restores the innate immune homeostasis of Drosophila by directly inhibiting Tab2 in Imd pathway","year":2024,"lang":"en","type":"article","venue":"Microbes and Infection","topic":"Invertebrate Immune Response Mechanisms","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto","funders":"Foundation Research Project of Jiangsu Province; National Natural Science Foundation of China; Graduate Research and Innovation Projects of Jiangsu Province; Natural Science Foundation for Young Scientists of Shanxi Province; Natural Science Foundation of Beijing Municipality; Natural Science Foundation of Jiangsu Province","keywords":"Innate immune system; Biology; Immune system; Immunity; Downregulation and upregulation; Homeostasis; Cell biology; Antimicrobial peptides; Immunology; Microbiology; Genetics; Gene; Antimicrobial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006141345,0.0001764934,0.0002393418,0.0002217363,0.0001772373,0.00004696012,0.0000818235,0.0002099358,0.00008129005],"category_scores_gemma":[0.00006187813,0.0001322986,0.000083293,0.0003383305,0.0001854573,0.0001211703,0.0001080091,0.0003441144,0.00005484029],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004855865,"about_ca_system_score_gemma":0.00004251314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001881134,"about_ca_topic_score_gemma":0.0001289998,"domain_scores_codex":[0.9987767,0.0002987354,0.0003725723,0.000261562,0.00002818152,0.0002621991],"domain_scores_gemma":[0.9995705,0.0001267599,0.00008838635,0.000166465,0.00003867787,0.000009143554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007540087,0.00004913698,0.000319439,0.00007206731,0.0000605703,0.00000287491,0.0007074074,0.000002836943,0.9845507,0.001074692,0.001201991,0.0118829],"study_design_scores_gemma":[0.0004106596,0.000177664,0.003971746,0.000247126,0.00002013982,0.00009672887,0.0001208882,0.00002209925,0.9642974,0.0003365231,0.0301509,0.0001481419],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9554382,0.04297215,0.0000713475,0.0003018568,0.0007097765,0.0002106703,0.00004337831,0.00006453742,0.0001881059],"genre_scores_gemma":[0.9974946,0.001632441,0.00001448923,0.00006325664,0.00002093437,0.00002629767,0.00007092688,0.00002493657,0.0006521433],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0420564,"threshold_uncertainty_score":0.539498,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007051791802463152,"score_gpt":0.2158947093794387,"score_spread":0.2088429175769756,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}