{"id":"W4401077890","doi":"10.7554/elife.97665","title":"T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type 1 cells","year":2024,"lang":"en","type":"article","venue":"eLife","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Praespero; Genome Alberta; Generalitat de Catalunya; Ministerio de Ciencia e Innovación; California State University, Chico; Centres de Recerca de Catalunya; Instituto de Salud Carlos III; Canadian Institutes of Health Research; Genome Canada","keywords":"Cell biology; Follicular phase; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001297476,0.0002370849,0.0001928374,0.0002414373,0.0001268235,0.0003149258,0.0001751372,0.0002006463,0.00196195],"category_scores_gemma":[0.0001769954,0.0001650757,0.000144379,0.000156449,0.0002987025,0.0002003303,0.0001936213,0.000408479,0.000762206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001691223,"about_ca_system_score_gemma":0.000127382,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003255432,"about_ca_topic_score_gemma":0.0005677782,"domain_scores_codex":[0.9998487,0.00001835092,0.000007384069,0.00004697942,0.00004001819,0.00003842643],"domain_scores_gemma":[0.9998305,0.00002847446,0.00004832291,0.00002611892,0.00002617298,0.00004043503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004172703,0.000006631714,0.0008809413,0.00001854289,0.000002521372,0.00003606448,0.00003227125,0.00001973327,0.9962854,0.0001391525,0.00002581619,0.002511119],"study_design_scores_gemma":[0.00002982296,0.0004505467,0.04369785,0.00001331968,0.00002394939,0.0008086884,0.0001539326,0.0005519406,0.9416149,0.0003906016,0.01225464,0.00000976213],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9859677,0.001887422,0.009010599,0.00005807558,0.00003768742,0.00003741657,0.0003746648,0.0002219144,0.002404412],"genre_scores_gemma":[0.9896897,0.0008471938,0.004003649,0.00007271309,0.00002869621,0.00003627458,0.0005765213,0.00004645474,0.004698835],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00196195,"threshold_uncertainty_score":0.006563365,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008450215810032953,"score_gpt":0.2281206311173567,"score_spread":0.2196704153073238,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}