{"id":"W4401101293","doi":"10.1503/cmaj.231588","title":"Free genetic testing is not free of clinical and ethical considerations","year":2024,"lang":"en","type":"article","venue":"Canadian Medical Association Journal","topic":"BRCA gene mutations in cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Saskatoon Medical Imaging; University of Saskatchewan; St. Paul's Hospital; Hospital for Sick Children; Providence Health Care","funders":"","keywords":"Genetic testing; Computer science; Genetic counseling; Key (lock); Medicine; Data science; Family medicine; Computer security; Genetics; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.08394413,0.0005295981,0.002064678,0.001039043,0.007095602,0.01013376,0.003101123,0.02378902,0.01369866],"category_scores_gemma":[0.218477,0.0007352413,0.0009389647,0.001046693,0.0346949,0.0076437,0.006650932,0.03844798,0.006139256],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.007378799,"about_ca_system_score_gemma":0.02852045,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01240162,"about_ca_topic_score_gemma":0.01947556,"domain_scores_codex":[0.8905218,0.0412905,0.005485293,0.007018921,0.0499752,0.005708341],"domain_scores_gemma":[0.7160349,0.1649195,0.01102607,0.02794396,0.04902549,0.0310501],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.0001040403,0.00009780885,0.001883794,0.0002296408,0.00007157301,0.0009898335,0.003880788,0.0001974026,0.0007954673,0.3053744,0.6205866,0.06578863],"study_design_scores_gemma":[0.0001006478,0.00007584244,0.002077754,0.001518373,0.0000437114,0.002415295,0.002283503,0.0003018217,0.0004665231,0.1691306,0.8214543,0.000131618],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.002949244,0.004844063,0.00335059,0.9332713,0.01057351,0.00007168725,0.0001184147,0.00009824592,0.04472287],"genre_scores_gemma":[0.1102175,0.003951926,0.007332179,0.839861,0.009828313,0.0002311557,0.0001933647,0.000219214,0.0281653],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.08394413,"threshold_uncertainty_score":0.4439443,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03097112488933471,"score_gpt":0.3303620208287434,"score_spread":0.2993908959394087,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}