{"id":"W4401103177","doi":"10.1002/etc.5955","title":"Inconsistent transcriptomic responses to hexabromocyclododecane in Japanese quail: a comparative analysis of results from four different study designs","year":2024,"lang":"en","type":"article","venue":"Environmental Toxicology and Chemistry","topic":"Toxic Organic Pollutants Impact","field":"Environmental Science","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Environment and Climate Change Canada; University of Saskatchewan; McGill University","funders":"U.S. Geological Survey; Genome Prairie; Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung; U.S. Environmental Protection Agency; McGill University; Génome Québec; U.S. Army Corps of Engineers; Environment and Climate Change Canada; Genome Canada; Government of Canada; National Science Foundation","keywords":"Hexabromocyclododecane; Transcriptome; Quail; Biology; Concordance; Coturnix japonica; Toxicology; Microarray; Physiology; Genetics; Computational biology; Gene; Gene expression; Ecology; Chemistry; Fire retardant","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008394355,0.0002351183,0.0002918121,0.0006038038,0.0003013352,0.0003408104,0.0001574013,0.0003240652,0.000466558],"category_scores_gemma":[0.0006136137,0.0001628847,0.000445037,0.0004359457,0.0004664875,0.0002370655,0.0003729654,0.0002185684,0.00006061521],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000339247,"about_ca_system_score_gemma":0.0003743004,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002985184,"about_ca_topic_score_gemma":0.01061891,"domain_scores_codex":[0.999534,0.00008729604,0.00006379621,0.0001825328,0.00008930349,0.0000432],"domain_scores_gemma":[0.9993083,0.0001736349,0.0001460298,0.00007033305,0.000227447,0.0000741871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003458371,0.00002208314,0.02623778,0.0001255659,0.00009300488,0.00003822591,0.0001602641,0.00004917324,0.9704887,0.00002435738,0.00001629584,0.002398764],"study_design_scores_gemma":[0.00001665764,0.001083604,0.8481485,0.00001568641,0.0004328191,0.0002106246,0.0007389639,0.0002903752,0.1480772,0.00007100886,0.0008910827,0.00002355308],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973224,0.0005332186,0.001274156,0.00003377785,0.000007689657,0.00003118785,0.0004911611,0.000007827156,0.000298605],"genre_scores_gemma":[0.992769,0.0005800987,0.003928204,0.0002085443,0.000006717739,0.0001819161,0.001405632,0.00001462446,0.0009052388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002985184,"threshold_uncertainty_score":0.005935609,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03106965776713188,"score_gpt":0.276668804184504,"score_spread":0.2455991464173721,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}