{"id":"W4401166766","doi":"10.1007/s00381-024-06504-7","title":"Future perspective of targeted treatments in pediatric low-grade glioma (pLGG): the evolution of standard-of-care and challenges of a new era","year":2024,"lang":"en","type":"review","venue":"Child s Nervous System","topic":"Glioma Diagnosis and Treatment","field":"Medicine","cited_by":8,"is_retracted":false,"has_abstract":false,"ca_institutions":"SickKids Foundation; Hospital for Sick Children; University of Toronto","funders":"","keywords":"Perspective (graphical); Standard of care; Medicine; Psychology; Computer science; Internal medicine; Artificial intelligence","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001022352,0.0005703456,0.001612059,0.001356447,0.0002110715,0.001371525,0.001017703,0.001343013,0.004882912],"category_scores_gemma":[0.00160719,0.0001653386,0.0008668036,0.001206206,0.0004314328,0.001585846,0.0005994364,0.002387061,0.001378348],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009830719,"about_ca_system_score_gemma":0.001830641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001841077,"about_ca_topic_score_gemma":0.005136856,"domain_scores_codex":[0.999732,0.00006996273,0.00004280204,0.00004496142,0.00007635951,0.00003387935],"domain_scores_gemma":[0.9991508,0.0004678155,0.0001128816,0.00001516694,0.0001984938,0.00005484342],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000130751,0.00006094988,0.0002103195,0.01738061,0.0001228173,0.0001662048,0.00004676043,0.0004970807,0.0007382726,0.004663601,0.0378381,0.9381446],"study_design_scores_gemma":[0.00006139897,0.0001904234,0.0008807646,0.01226325,0.0003279695,0.0009961085,0.0001068566,0.0002732964,0.0002367605,0.003690701,0.9809471,0.00002536333],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007362256,0.998156,0.0001064438,0.0008865802,0.0002347138,0.000002940048,0.00002054522,0.000007409402,0.0005117349],"genre_scores_gemma":[0.0006797687,0.9978124,0.0002759292,0.0006518873,0.0002675538,0.000005018886,0.00003102336,0.000001750849,0.0002746362],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004882912,"threshold_uncertainty_score":0.01633495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01893175370126607,"score_gpt":0.2863745897733269,"score_spread":0.2674428360720608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}