{"id":"W4401170271","doi":"10.1136/annrheumdis-2024-eular.1460","title":"OP0272 SINGLE-CELL ANALYSIS OF PERIPHERAL BLOOD MONONUCLEAR CELLS IDENTIFIES IMMUNE SIGNATURES AT DIFFERENT STAGES OF ACTIVE RHEUMATOID ARTHRITIS","year":2024,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Lupus Erythematosus Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Rheumatoid arthritis; Peripheral blood mononuclear cell; Immune system; Peripheral blood; Immunology; Cell; Peripheral; Medicine; Biology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002011881,0.0002635583,0.0004620917,0.0006807908,0.0002456586,0.0007199734,0.0001788342,0.0005137417,0.002604974],"category_scores_gemma":[0.0002359436,0.0001474423,0.0002339952,0.0003968346,0.0002034906,0.0002053314,0.0002273794,0.0004775042,0.0008579211],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001141207,"about_ca_system_score_gemma":0.0001290922,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005686995,"about_ca_topic_score_gemma":0.001036261,"domain_scores_codex":[0.9997913,0.00002344551,0.00001445736,0.00005148133,0.00004395045,0.00007541661],"domain_scores_gemma":[0.9998941,0.00002663856,0.0000194736,0.00001047408,0.00001902552,0.00003026206],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001571818,0.00006761222,0.01674884,0.00006022118,0.00001913189,0.0001985898,0.00008394327,0.00006811185,0.974507,0.00004114729,0.0001925536,0.006441014],"study_design_scores_gemma":[0.0001481595,0.001640749,0.7384803,0.00002987417,0.0001774894,0.002117131,0.000604358,0.002079186,0.251254,0.0002226999,0.003214079,0.00003184857],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960783,0.000872609,0.0009831529,0.00004818722,0.00002060856,0.00002622974,0.0007332701,0.00003443073,0.001203212],"genre_scores_gemma":[0.9958687,0.0003907071,0.001005253,0.00009626189,0.00003873253,0.00006852753,0.0007646537,0.00001504756,0.001752154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002604974,"threshold_uncertainty_score":0.008714437,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02443443527857258,"score_gpt":0.2882770274196235,"score_spread":0.2638425921410509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}